Protein Alignment FER and F22B3.8

DIOPT Version :9

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_502160.4
• Gene: F22B3.8 / 184809
• WormBaseID: WBGene00009039
• Length: 497
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 132/495 - (26%)
• Similarity: 217/495 - (43%)
• Gaps: 121/495 - (24%)

  Fly   907 ELDENSDRDIDNDEEEEDSASDDVL--SMKDHCYCVPSLAASISLSTNRP----LYEEEWFHGVL 965
            |..|.::|..|.     .|.|:.|:  ...|..|.......|:...||..    |...::|||.:
 Worm    12 ETTEKTERTTDG-----SSISNSVMINFPDDSMYQNVEKTKSVGRVTNEMIDNYLLRYQFFHGFV 71

  Fly   966 PREEVVRLLNNDGDFLVRETIRNEESQ--------------------IVLSV------------- 997
            .:|..:.||..:||||:|.:.:.|::.                    :||||
 Worm    72 LQELQLILLKTNGDFLLRLSHQPEKNAKKPTTPDKSATDPIPLTRVILVLSVNITQKTGTTRSFY 136

  Fly   998 -------CWNGHKH-FIVQTTGEGNF-----RFEGPPFASIQELIMHQYHSELPVTVKSGAI-LR 1048
                   ..|...| ||.:|.|:...     ||:   |.:|.|||  .|:...|:...:..: |:
 Worm   137 GDLEDVKKENMDMHLFIEETAGKWTSFYIERRFK---FPTIDELI--NYYKVNPICYHNTRVFLK 196

  Fly  1049 RPVCRERWELSNDDVVLL-ERIGRGNFGDVYKAKLKS----------TKLDVAVKTCRMTLPDEQ 1102
            ||:..:.|||..:.:.:. :::|.|.||.||..:...          ...||||||.:   .|:.
 Worm   197 RPIVLQDWELRAEGIDMTPKKLGEGAFGIVYLGRWAQPFSVDQKEFHKWCDVAVKTVK---NDDS 258

  Fly  1103 KRKFLQ---EGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMG 1164
            :...|:   |.|:..|..|.|::...|:.:.|:|||:|.|.     ...||:|:.  ::..:::.
 Worm   259 RAALLEVMHEARLQLQLRHKNVLAFRGVFLLKKPIMLVSEF-----CENYLQKSK--VSVDEKLR 316

  Fly  1165 MCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSREEEEYIVSDGMKQIPVKWTAP 1229
            .|..::.|:.|:..|..||||||.||.||..:.:.||:|||:::....|.:....| |||::.||
 Worm   317 FCLGSSCGLEYIHFKGLIHRDLATRNILVSADKTPKIADFGLAKHASSYKMRKATK-IPVRYLAP 380

  Fly  1230 EALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTP------EE 1288
            |.|:...|::..||:::|:::||||:.|..||  |.....:|.:       .||:|.      :|
 Worm   381 ETLSSFVYSTKTDVYTFGLVIWEIFANGQEPY--MKAQPHQECV-------APKNTQLRGRHIKE 436

  Fly  1289 MYR------------LMLQCWAA------DAESRPHFDEI 1310
            :.|            :.||.:.|      |.:.||...|:
 Worm   437 LIRKELFVKFNQEAPVALQQYVAAKLFVVDDKKRPDMPEV 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	31/135 (23%)
		TyrKc	1063..1311	CDD:197581	82/286 (29%)
		PTKc_Fes_like	1067..1315	CDD:270637	82/281 (29%)
F22B3.8	NP_502160.4	SH2	64..186	CDD:214585	30/126 (24%)
		S_TKc	216..476	CDD:214567	81/279 (29%)
		PTKc	216..>412	CDD:270623	66/206 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	1	1.100	-	-	O	PTHR24418
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810