DRSC/TRiP Functional Genomics Resources

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Protein Alignment FER and Ntrk3

DIOPT Version :9

Sequence 1:NP_524288.3 Gene:FER / 41118 FlyBaseID:FBgn0000723 Length:1325 Species:Drosophila melanogaster
Sequence 2:XP_036008659.1 Gene:Ntrk3 / 18213 MGIID:97385 Length:850 Species:Mus musculus


Alignment Length:306 Identity:99/306 - (32%)
Similarity:156/306 - (50%) Gaps:54/306 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly  1062 DVVLLERIGRGNFGDVYKAK---LKST--KLDVAVKTCR-MTLPDEQKRKFLQEGRILKQYDHPN 1120
            |:||...:|.|.||.|:.|:   |..|  |:.||||..: .||  ..::.|.:|..:|....|.:
Mouse   537 DIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTL--AARKDFQREAELLTNLQHEH 599

  Fly  1121 IVKLIGICVQKQPIMIVMELVLGGSLLTYLR-----------------KNSNGLTTRQQMGMCRD 1168
            |||..|:|....|:::|.|.:..|.|..:||                 |...||:  |.:.:...
Mouse   600 IVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLS--QMLHIASQ 662

  Fly  1169 AAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSRE---------------------EEE 1212
            .|:||.||.|::.:|||||.|||||.....|||.||||||:                     :::
Mouse   663 IASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYREGPCQKGPFNVSWQQQ 727

  Fly  1213 YIVSD------GMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARE 1271
            .:.:.      |...:|::|..||::.:.|:|:..||||:|:::||||:.|..|:..::|:...|
Mouse   728 RLAASAASTVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIE 792

  Fly  1272 RIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDAL 1317
            .|..|..:..|:..|:|:|.:||.||..:.:.|.:..|||.::.||
Mouse   793 CITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 838

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FERNP_524288.3 F-BAR_Fes_Fer 7..243 CDD:153341
SH2_Fps_family 953..1039 CDD:198224
TyrKc 1063..1311 CDD:197581 94/297 (32%)
PTKc_Fes_like 1067..1315 CDD:270637 94/297 (32%)
Ntrk3XP_036008659.1 LRR_8 103..160 CDD:404697
leucine-rich repeat 105..128 CDD:275378
leucine-rich repeat 129..151 CDD:275378
leucine-rich repeat 152..164 CDD:275378
TPKR_C2 163..208 CDD:407151
ig 214..299 CDD:395002
Ig strand A' 218..221 CDD:409353
Ig strand B 226..234 CDD:409353
Ig strand C 240..244 CDD:409353
Ig strand D 254..262 CDD:409353
Ig strand E 266..271 CDD:409353
Ig strand F 279..288 CDD:409353
Ig strand G 291..301 CDD:409353
IgI_TrKABC_d5 304..396 CDD:409360
Ig strand B 319..323 CDD:409360
Ig strand C 332..336 CDD:409360
Ig strand E 361..365 CDD:409360
Ig strand F 375..380 CDD:409360
Ig strand G 388..391 CDD:409360
PTKc_TrkC 532..843 CDD:270676 99/306 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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