Protein Alignment FER and mlk-1

DIOPT Version :9

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_001300151.1
• Gene: mlk-1 / 178895
• WormBaseID: WBGene00003374
• Length: 1059
• Species: Caenorhabditis elegans
• Alignment Length: 440
• Identity: 106/440 - (24%)
• Similarity: 176/440 - (40%)
• Gaps: 123/440 - (27%)

  Fly   922 EEDSASDDVLSMKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLPREEVVRLLNNDGDFLVRETI 986
            |.::..||.|::.     :.::...:::.||    |:.|:.|.|
 Worm    79 EYEAQKDDELNLP-----LGAIITLVTVETN----EDGWYRGEL--------------------- 113

  Fly   987 RNEESQIVLSVCWNGH-----KHFIVQTTGEGNF-RFEGPPFASIQELIMHQYHSELPVTVKS-- 1043
                         ||.     .::..:.|.:.|. .|:       |:.||      |||.|::
 Worm   114 -------------NGKVGLFPSNYAREVTYKDNLVEFK-------QDEIM------LPVAVRTLS 152

  Fly  1044 ------GA---ILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLP 1099
                  ||   :.:..: :.:.||.|.      |:|.. .||..||.||......:.....:...
 Worm   153 DCQIGHGATATVFKMDI-KIKKELQNG------RMGEA-VGDQMKAALKRFNRHASNFRADVVST 209

  Fly  1100 DEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRK-NSNGLTTRQQM 1163
            |||..:..:|..::....|.|||:|:|||::.....:::||..|.||....|. ||:...   .:
 Worm   210 DEQLEQLKREANLVNGLSHNNIVRLLGICLEDPYFGLLLELCEGSSLRNVCRNLNSDAAI---PL 271

  Fly  1164 GMCRD----AAAGMRYLESKNCIHRDLAARNCLVDLE-------------------------HSV 1199
            |:..|    .|.||.||..:..:||||.|.|.||..|                         ..:
 Worm   272 GVLIDWATQVAEGMEYLTKQGYVHRDLKADNVLVKEEVCLCMDEEMFQYAYCLKCGKRPFDKLQL 336

  Fly  1200 KISDFGMSREEEEYIVSDGMKQIPV---KWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPY 1261
            ||:|||::|:    :.:|..:....   .|.||||...|.::...||||||:::||:.:: :.||
 Worm   337 KITDFGVTRK----MTADANRFSTAGTYAWLAPEAFKEGTWSEASDVWSYGVVLWELLTR-EEPY 396

  Fly  1262 SG-MTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEI 1310
            .| :..:.|.:..:.|..:....|.|:...:||..||..:...||.|..:
 Worm   397 QGHIPATIAFQIANKGQNLSIGDSCPDRWKKLMQDCWNLEPNFRPKFSTL 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	13/91 (14%)
		TyrKc	1063..1311	CDD:197581	79/282 (28%)
		PTKc_Fes_like	1067..1315	CDD:270637	79/278 (28%)
mlk-1	NP_001300151.1	SH3	75..124	CDD:302595	12/87 (14%)
		STYKc	153..450	CDD:214568	84/310 (27%)
		PKc_like	156..446	CDD:304357	84/305 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900