DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and F11E6.8

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_001255960.1	Gene:	F11E6.8 / 178530	WormBaseID:	WBGene00008711	Length:	442	Species:	Caenorhabditis elegans

Alignment Length:	278	Identity:	99/278 - (35%)
Similarity:	165/278 - (59%)	Gaps:	22/278 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly  1058 LSNDDVVLLERIGRGNFGDVYKAKLKSTK---LDVAVKTCRMTLPDEQKR------KFLQEGRIL 1113
            |.::.|||...:|:|.||:||:.:::...   :.||||    ||..|:.|      |||:||.::
Worm   131 LPSEAVVLETIVGKGYFGNVYRGRMRDPAGRLIPVAVK----TLKGERARDIAHIEKFLREGVVM 191

  Fly  1114 KQYDHPNIVKLIGICVQK--QPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYL 1176
            |..|||:::.|:||.:..  .| .:|:..:.||.|.||:...:..|...:.:......|.||.||
Worm   192 KHLDHPHVLSLLGISISPAGNP-WVVLPYMEGGDLKTYIADPNRALCVLELLDFAHQVAQGMSYL 255

  Fly  1177 ESKNCIHRDLAARNCLVDLEHSVKISDFGMS---REEEEYI--VSDGMKQIPVKWTAPEALNFGK 1236
            .:::.:|||||||||::..:..||::|||::   .::|.||  ...|..::|:||.|||:|...:
Worm   256 AAQHFVHRDLAARNCMISADRIVKVADFGLAVDLLDKESYIDESETGPARLPLKWLAPESLRDRR 320

  Fly  1237 -YTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAAD 1300
             ::|..||||:|:||||:.::..:||..::|::.|..::||.|:|.|...|:.:|.||..||.:.
Worm   321 VFSSATDVWSFGVLMWELLTRAASPYGEVSNTKVRHYLETGMRLPQPTHCPDIIYDLMQCCWRST 385

  Fly  1301 AESRPHFDEIYNVVDALI 1318
            .|.||.|..:.:.:.||:
Worm   386 PEDRPDFVFLSHRLRALL 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	96/264 (36%)
		PTKc_Fes_like	1067..1315	CDD:270637	93/264 (35%)
F11E6.8	NP_001255960.1	PTKc	141..400	CDD:270623	93/263 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910