DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and ver-1

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_497162.2	Gene:	ver-1 / 175182	WormBaseID:	WBGene00006894	Length:	1083	Species:	Caenorhabditis elegans

Alignment Length:	278	Identity:	82/278 - (29%)
Similarity:	134/278 - (48%)	Gaps:	34/278 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1056 WELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQY-DHP 1119
            :|...|.:.:||.||.|:||.|.:..||.||..||||:.........::..::|.:::... .||
Worm   796 FEFHKDSLEILEPIGSGHFGVVRRGILKGTKTVVAVKSSSYRSSIGFQKVIVEELKLMSAIPKHP 860

  Fly  1120 NIVKLIGIC---VQKQPIMIVMELVLGGSLLTYL----------------------RKNSNGLTT 1159
            |::.|:|..   ::...:.|:||.:.||:|..:|                      |.:.|.|:|
Worm   861 NVLALVGAITKNLRHGELYILMEYIDGGNLRDFLQQRRNVFIDELHDNFDENIPLIRPDFNSLST 925

  Fly  1160 RQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSREEEEYIVSDGMKQIPV 1224
            ...:|:....|.||.:|.:..|:|.:|..|..|:....:::|:|:|:...:.        |...:
Worm   926 TDLVGIAHQIANGMEWLGNVPCVHGNLCCRKVLISKTKTIRITDYGVGDRQR--------KSSSM 982

  Fly  1225 KWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEM 1289
            :|.||||:....::|..||||:||.::|||:.|.|||.........:.|..|.|...|:..|..:
Worm   983 RWMAPEAIEHQMFSSKSDVWSFGICLYEIFTLGGTPYPTCVTENILKHIKNGSRNLQPEYCPSAL 1047

  Fly  1290 YRLMLQCWAADAESRPHF 1307
            |.||..||.|..:.||.|
Worm  1048 YDLMQLCWRAPPQDRPKF 1065

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	80/271 (30%)
		PTKc_Fes_like	1067..1315	CDD:270637	79/267 (30%)
ver-1	NP_497162.2	Ig	<294..331	CDD:299845
		ig	576..652	CDD:278476
		IG_like	578..654	CDD:214653
		IG_like	660..731	CDD:214653
		IGc2	674..722	CDD:197706
		Pkinase_Tyr	803..1072	CDD:285015	80/271 (30%)
		PTKc	807..1073	CDD:270623	79/267 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910