DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and kin-16

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_496017.1	Gene:	kin-16 / 174499	WormBaseID:	WBGene00002200	Length:	495	Species:	Caenorhabditis elegans

Alignment Length:	335	Identity:	98/335 - (29%)
Similarity:	152/335 - (45%)	Gaps:	66/335 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1053 RERWELSNDDVVLLERIGRGNFGDVYKAKL----------KSTKLDVAVKTCRMTLPDEQKRKFL 1107
            ::::|::::::.....:|.||||.|.|..|          |..:|.||||:........|.....
Worm   130 KKQYEIASENLENKSILGSGNFGVVRKGILKMASPKNEEEKKMRLTVAVKSAANCYDISQTSMLA 194

  Fly  1108 QEGRILKQYDH-PNIVKLIGIC---VQKQPIMIVMELVLGGSLLTYL------------------ 1150
            .|.|::..... ||::.|:|..   ::|..::||.|.:..|.:..||
Worm   195 AELRLMCSIGRFPNVLALVGAVTSELRKGRLLIVTEYIDCGDIRKYLIDHRNVFQDHLIEDKTEP 259

  Fly  1151 ----------RKN-----------------SNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAA 1188
                      |||                 .:.|||...:......|.||:||.|...:|||||.
Worm   260 DSYLTPISAKRKNYVFKNTDENSDYVIKESLDSLTTSDLLSFGLQIANGMQYLASIPMVHRDLAL 324

  Fly  1189 RNCLVDLEHSVKISDFGMSR--EEEEYIVSDGMKQ--IPVKWTAPEALNFGKYTSLCDVWSYGIL 1249
            ||.|:....:::|:||||:|  |.:.|.:....|.  :||:|.:|||.:..|:|...||||:||.
Worm   325 RNVLLKKNKTIRIADFGMARTHENKSYYIPQKTKDAPVPVRWMSPEAFDTMKFTEKSDVWSFGIC 389

  Fly  1250 MWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVV 1314
            ::|||:.|..||..:.:.|..|.:.:|.|.|.|:....|:|.||..||....|.||:|.   |.|
Worm   390 LYEIFTLGQLPYPDVPSERIYEYMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNFS---NCV 451

  Fly  1315 DALILRLDNS 1324
            :..|..:..|
Worm   452 EYFIGHMKKS 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	93/310 (30%)
		PTKc_Fes_like	1067..1315	CDD:270637	94/310 (30%)
kin-16	NP_496017.1	STYKc	140..454	CDD:214568	95/316 (30%)
kin-16	NP_496017.1	PTKc	145..454	CDD:270623	95/311 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910