DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FER and Matk

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	XP_006513357.1	Gene:	Matk / 17179	MGIID:	99259	Length:	506	Species:	Mus musculus

Alignment Length:	382	Identity:	132/382 - (34%)
Similarity:	195/382 - (51%)	Gaps:	36/382 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   948 SLSTNRPLYEEEWFHGVLPREEVVRLLN--NDGDFLVRETIRNEESQIVLSVCWNGHKHFIVQTT 1010
            :|||:..|....||||.:..:|.::.|.  .||.|||||:.|:....::.........|:.| ..
Mouse   109 ALSTDPKLSLMPWFHGKISGQEAIQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRV-LH 172

  Fly  1011 GEGNFRF-EGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCRER---------------WELS 1059
            .:|:... |...|.::.:::.|       .|...|||..:.|...|               |.|.
Mouse   173 RDGHLTIDEAVCFCNLMDMVEH-------YTKDKGAICTKLVKPRRKQGAKSAEEELAKAGWLLD 230

  Fly  1060 NDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKL 1124
            ...:.|..:||.|.||.|.:.:....|  ||||..:.   |...:.||.|..::.:..|.|:|:|
Mouse   231 LQHLTLGAQIGEGEFGAVLQGEYLGQK--VAVKNIKC---DVTAQAFLDETAVMTKLQHRNLVRL 290

  Fly  1125 IGICVQKQPIMIVMELVLGGSLLTYLRKNSNGL-TTRQQMGMCRDAAAGMRYLESKNCIHRDLAA 1188
            :|: :....:.||||.|..|:|:.:||.....| :|.|.:......|.||.|||||..:||||||
Mouse   291 LGV-ILHHGLYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAA 354

  Fly  1189 RNCLVDLEHSVKISDFGMSREEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEI 1253
            ||.||..:...|:||||:::.|.:.:.|   .::||||||||||..|:::|..||||:|:|:||:
Mouse   355 RNILVSEDLVAKVSDFGLAKAERKGLDS---SRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEV 416

  Fly  1254 FSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEI 1310
            ||.|..||..|:.....|.::.||||..|...|..::.||..||.|:...||.|.:|
Mouse   417 FSYGRAPYPKMSLKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKI 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	21/88 (24%)
		TyrKc	1063..1311	CDD:197581	100/249 (40%)
		PTKc_Fes_like	1067..1315	CDD:270637	99/245 (40%)
Matk	XP_006513357.1	SH3	49..107	CDD:388381
		SH2_csk_like	117..214	CDD:198190	26/104 (25%)
		PKc_like	227..480	CDD:389743	102/256 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810