Protein Alignment FER and src-1

DIOPT Version :9

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_001364829.1
• Gene: src-1 / 171722
• WormBaseID: WBGene00005077
• Length: 537
• Species: Caenorhabditis elegans
• Alignment Length: 492
• Identity: 167/492 - (33%)
• Similarity: 253/492 - (51%)
• Gaps: 95/492 - (19%)

  Fly   902 ESSSGELDENSDRDIDND---------EEEE--------DSASD--------DVLSMKDHCYC-- 939
            |.:..:|:..||..:.|.         :|.|        ||.:|        |.:.:.||..|
 Worm    48 EGTISQLNGTSDGMMGNGRGGGGGGGAQERETLVALYPYDSRADGDLSFQKGDAMYLLDHSNCDW 112

  Fly   940 -------------VPSLAASISLSTNRPLYEEEWFHGVLPREEVVRLLNND----GDFLVRE--- 984
                         ||    ...::..:.:..|||:.|.:||....||:.:.    |.||:||
 Worm   113 WYVRHQRTGQTGYVP----RNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREA 173

  Fly   985 -------TIRNEESQIVLSVCWNGH--KHFIVQTT--GEGNFRFEGPPFASIQELIMHQYHSELP 1038
                   |||:.:.|      .||.  ||:.::..  .:|.|......|.|:|||:  :|:|::|
 Worm   174 DTREFALTIRDTDDQ------RNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELV--RYYSDVP 230

  Fly  1039 ------VTVKSGAIL-RRP----VCRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVK 1092
                  :|..:..:. .||    ..::.||:..:.:.|..::|.||||:|:..|.:.. ::||:|
 Worm   231 DGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGI-VEVAIK 294

  Fly  1093 TCRM-TLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNG 1156
            |.:. |:..|   .||||.:|:||.||||:|||..:|.:::|..|:.|.::.||||.|||.:.:.
 Worm   295 TMKPGTMSPE---AFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGST 356

  Fly  1157 LTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHS----VKISDFGMSR---EEEEYI 1214
            |..:..:.|....|.||.|||.:..:||||||||.||..:.|    ||::|||::|   ||:.|.
 Worm   357 LGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYE 421

  Fly  1215 VSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRM 1279
            ...|.| .|:|||||||...|.:|...||||||||::||.:||..||.||.|....|:::.||||
 Worm   422 ARTGAK-FPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRM 485

  Fly  1280 PTPKSTPEEMY-RLMLQCWAADAESRPHFDEIYNVVD 1315
            |.|:..||::| .::|:||....:.||.||.:|:..|
 Worm   486 PMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFD 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	31/109 (28%)
		TyrKc	1063..1311	CDD:197581	113/256 (44%)
		PTKc_Fes_like	1067..1315	CDD:270637	113/256 (44%)
src-1	NP_001364829.1	SH3_Src_like	79..130	CDD:212779	9/54 (17%)
		SH2_Src_family	138..240	CDD:199827	32/109 (29%)
		PTKc_Src_like	270..522	CDD:270630	113/256 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910