DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FER and Tesk2

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	NP_596887.1	Gene:	Tesk2 / 170908	RGDID:	619984	Length:	570	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	76/273 - (27%)
Similarity:	135/273 - (49%)	Gaps:	18/273 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly  1058 LSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIV 1122
            |::.|....|:||.|.|.:|:|.:.:::...:|:|   |......:...|:|.:::.:..||||:
  Rat    53 LTSLDDFTREKIGSGFFSEVFKVRHRASGQVMALK---MNTLSSNRANLLKEMQLMNRLSHPNIL 114

  Fly  1123 KLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLA 1187
            :.:|:||.:..:..:.|.:..|:|...|..|.. |....::.:..|.|.|:.||..|...||||.
  Rat   115 RFMGVCVHQGQLHALTEYINSGNLEQLLDSNLY-LPWTVRVKLAYDIAVGLSYLHFKGIFHRDLT 178

  Fly  1188 ARNCLVDLE---HSVKISDFGMSREEEEYIVSDGMKQIPVK----WTAPEALNFGKYTSLCDVWS 1245
            ::|||:..:   :|..::|||::.:..:  .|.|.:::.|.    |.|||.|....|....||:|
  Rat   179 SKNCLIKRDENGYSAVVADFGLAEKIPD--ASIGSEKLAVVGSPFWMAPEVLRDEPYNEKADVFS 241

  Fly  1246 YGILMWEIFSK--GDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFD 1308
            |||::.||.::  .|..|...|.:..   :|...........|.:..:|...|...|.:.||.|:
  Rat   242 YGIILCEIIARIQADPDYLPRTENFG---LDYDAFQHMVGDCPSDFLQLTFNCCNMDPKLRPSFE 303

  Fly  1309 EIYNVVDALILRL 1321
            ||...::.::.||
  Rat   304 EIGKTLEEIMSRL 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	71/256 (28%)
		PTKc_Fes_like	1067..1315	CDD:270637	72/256 (28%)
Tesk2	NP_596887.1	PKc_TESK	64..316	CDD:271057	71/260 (27%)
Tesk2	NP_596887.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	513..570
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910