| Sequence 1: | NP_524288.3 | Gene: | FER / 41118 | FlyBaseID: | FBgn0000723 | Length: | 1325 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_034324.2 | Gene: | Fes / 14159 | MGIID: | 95514 | Length: | 822 | Species: | Mus musculus |
| Alignment Length: | 1326 | Identity: | 340/1326 - (25%) |
|---|---|---|---|
| Similarity: | 498/1326 - (37%) | Gaps: | 522/1326 - (39%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MGFSSALQSRAAHEALIVRQDAELRLMETMKRSIQMKAKCDKEYAISLTAVAQQGLKIDRADEMQ 65
Fly 66 GSLISKSWRSYMDELDHQAKQFKFNAEQLEV-VCDKLTHLSQDKRKARKAYQEEHAKIAARLNHL 129
Fly 130 TDEVVRK-KSEYQKHLEGYKALRTRFEENYIKAPSRSGRKLDDVRDKYQKACRKLHLTHNEYVLS 193
Fly 194 ITEAIEVEKDFRNVLLPGLLEHQQSVQESFILLWRNILQEAAQYGDLTADKYKEIQKRIDTVIGS 258
Fly 259 INPTEEYGEFTEKYKTSPTTPLLFQFDETLIQD----IPGKLQSSTLTVDNLTVDWLRNRLQELE 319
Fly 320 GAVRDCQEKQMKMIEHVNGGSPVANGSIISNGSNTSNGIQSNKDSLCRQSKDLNALRCQEKQKQK 384
Fly 385 LVDMIKCALNEVGCEELPSGCDDDLTLEQNFIENGYNNEQQRSNSTSSPGLGIMNELMRRGGVLT 449
Fly 450 LLRGRGRHFKRKSTPQPATPMTRSRQGRFNKLQPRSQSLGSLSVIRDGNGPSPARYEPITNHRLR 514
Fly 515 QAASVHYLGEEIATSSTNPPDLTRLRRTQCSMLCLGEDEEPVVLASPAPLTQLTAAVLTNTNNNH 579
Fly 580 IYADLELDKKKDTSPSPECKGEQIQPKKEQIRIEINQTAPQNSIDAHLDRIDELNRVLDDRLKRT 644
Fly 645 LQPSDDVNAIESAEENHIQTRKLAKDPDSQTKRSSSSSSECRSSKDTSHSKKRSLSFSQKSISNI 709
Fly 710 FSNLKEFSKSPLVRMGKNHILNEEQDAKRTQPSQHHHSSGSDCPTNSSSSSSNNNNNNKNTSSNS 774
Fly 775 NHSASQSTIITSTITTTITTTTTTTPSKENSRLKFKVPKIQKKSKAIRNTFRSKLLNFQLKRSKP 839
Fly 840 CKQCTKRRRIHPSKSVFDFAKEFEVEQPAGSAADEQFCNCPPAGQKPVKPSVQISGHKDHPFESS 904
Fly 905 SGELDENSDRDIDNDEEEEDSASDDVLSMKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLPREE 969
Fly 970 VVRLLNNDGDFLVRETIRNEESQIVLSVCWNGH-KHFIVQTTGEGNFRFEGPPFASIQELIMHQY 1033
Fly 1034 HSELPVTVKSGAILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTL 1098
Fly 1099 PDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQM 1163
Fly 1164 GMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSREEEE--YIVSDGMKQIPVKW 1226
Fly 1227 TAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYR 1291
Fly 1292 LMLQCWAADAESRPHF----DEIYNV 1313 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| FER | NP_524288.3 | F-BAR_Fes_Fer | 7..243 | CDD:153341 | 63/237 (27%) |
| SH2_Fps_family | 953..1039 | CDD:198224 | 41/86 (48%) | ||
| TyrKc | 1063..1311 | CDD:197581 | 148/253 (58%) | ||
| PTKc_Fes_like | 1067..1315 | CDD:270637 | 146/253 (58%) | ||
| Fes | NP_034324.2 | Important for interaction with membranes containing phosphoinositides. /evidence=ECO:0000250 | 1..300 | 87/304 (29%) | |
| F-BAR_Fes | 7..239 | CDD:153369 | 63/237 (27%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 392..420 | 15/167 (9%) | |||
| SH2_Fps_family | 453..537 | CDD:198224 | 41/86 (48%) | ||
| PKc_like | 564..814 | CDD:389743 | 145/249 (58%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 312 | 1.000 | Domainoid score | I1309 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0194 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 545 | 1.000 | Inparanoid score | I1145 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000006 | |
| OrthoInspector | 1 | 1.000 | - | - | otm44118 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100013 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24418 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3894 |
| SonicParanoid | 1 | 1.000 | - | - | X1749 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 12 | 11.850 | |||||