DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and AgaP_AGAP008009

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	XP_317454.4	Gene:	AgaP_AGAP008009 / 1277939	VectorBaseID:	AGAP008009	Length:	519	Species:	Anopheles gambiae

Alignment Length:	265	Identity:	75/265 - (28%)
Similarity:	132/265 - (49%)	Gaps:	17/265 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly  1052 CRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQY 1116
            ||.|         |...:..|.||.||:.....:: :|.|||........|....|.||..|...
Mosquito   251 CRVR---------LSSLLQEGTFGRVYRGSYNDSQ-EVLVKTVGPHASQVQVSLLLHEGMSLYGA 305

  Fly  1117 DHPNIVKLIGICVQKQ--PIMIVMELVLGGSLLTYLRKN-SNGLTTRQQMGMCRDAAAGMRYLES 1178
            .||.|:.::|:.:...  |.::.:......:|..:|::. :..|||.|.:.:....|..:.:|.|
Mosquito   306 QHPGILSVLGVSIDDHTAPFLLYLAPENTRNLKIFLQEPVARTLTTIQIVKIQLQLAQALGHLHS 370

  Fly  1179 KNCIHRDLAARNCLVDLEHSVKISDFGMSRE---EEEYIVSDGMKQIPVKWTAPEALNFGKYTSL 1240
            ...||:|:|||||::|.:..||::|..:||:   .:.|.:.|...: |:||.|.|::.|.:::..
Mosquito   371 HGVIHKDIAARNCVIDDQLRVKLADNSLSRDLFPGDYYCLGDSENR-PIKWLALESIQFKQFSES 434

  Fly  1241 CDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRP 1305
            .|.|::|:||||:.:....||:.:........:..|||:..|.:.|:|::.:|..||......||
Mosquito   435 SDTWAFGVLMWELCTLARQPYAEVDPFEMEHYLRDGYRLSQPINCPDELFAIMAYCWTMMPMERP 499

  Fly  1306 HFDEI 1310
            .|:::
Mosquito   500 SFEQL 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	72/254 (28%)
		PTKc_Fes_like	1067..1315	CDD:270637	71/250 (28%)
AgaP_AGAP008009	XP_317454.4	WIF	1..115	CDD:280237
		PKc_like	246..515	CDD:304357	75/265 (28%)
		Pkinase_Tyr	253..508	CDD:285015	73/263 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910