DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and AgaP_AGAP013516

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	XP_003436321.1	Gene:	AgaP_AGAP013516 / 11175763	VectorBaseID:	AGAP013516	Length:	604	Species:	Anopheles gambiae

Alignment Length:	263	Identity:	88/263 - (33%)
Similarity:	134/263 - (50%)	Gaps:	16/263 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly  1061 DDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLI 1125
            :::..:..:|:|::|.|.|||.::..  ||||  .|.:..||  .|..|...|.:..||||::|.
Mosquito    15 NEIEQIATVGKGSYGTVIKAKWRNKY--VAVK--YMEVLTEQ--AFTAEVSHLSRVAHPNIIELY 73

  Fly  1126 GICVQKQPIMIVMELVLGGSLLTYLRKNSNGL-TTRQQMGMCRDAAAGMRYLES---KNCIHRDL 1186
            |.|.:|....:|||...||||...|......: |....|...|..|.|:.||..   :..|||||
Mosquito    74 GACTEKPNFCLVMEYADGGSLHKVLHSRPRPVYTAAHAMSWARQCAEGVAYLHDMTPRPMIHRDL 138

  Fly  1187 AARNCLVDLEHSV-KISDFGMSREEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILM 1250
            ...|.|:....:| ||.|||...::...:.::   :....|.|||......||..|||:|:||::
Mosquito   139 KPPNLLLVNNGTVLKICDFGTVTDKSTLMTNN---KGSAAWMAPEVFEGSSYTEKCDVFSWGIIL 200

  Fly  1251 WEIFSKGDTPYSGMTNSRA-RERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVV 1314
            ||:.:: :.|:..:..|.| ..|:..|.|.|.....|:.:.:||::||..|..|||...|:.||:
Mosquito   201 WEVIAR-EQPFKHIDTSYAIMWRVHQGSRPPLIDHCPKPIEQLMVRCWDKDPISRPSMKEVVNVM 264

  Fly  1315 DAL 1317
            :||
Mosquito   265 NAL 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	84/253 (33%)
		PTKc_Fes_like	1067..1315	CDD:270637	86/253 (34%)
AgaP_AGAP013516	XP_003436321.1	STKc_TAK1	23..272	CDD:270960	88/255 (35%)
AgaP_AGAP013516	XP_003436321.1	STYKc	24..264	CDD:214568	85/249 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910