DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and LOC101886393

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	XP_005172193.3	Gene:	LOC101886393 / 101886393	-ID:	-	Length:	977	Species:	Danio rerio

Alignment Length:	453	Identity:	121/453 - (26%)
Similarity:	179/453 - (39%)	Gaps:	122/453 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   904 SSGELDENSDRDIDNDE----------EEEDSASDDVLSMKDHCYCVPSLAASISLSTNRPLYEE 958
            |.|.|.:|.|:......          :.|.:..|::...|.....|.||.:.||       .:|
Zfish     9 SRGTLWKNLDQQTQKGSFSNPVWTALFDYEAAGKDELTLRKGDLVEVLSLDSEIS-------GDE 66

  Fly   959 EWFHGVLPREEVVRLLNNDGDFLVRETIRNEESQIVLSVCWNGHKHFIVQTTGEGNFRFEGPPFA 1023
            .|:.|        ::.|..|.|                    ...:...:.:|.|......||..
Zfish    67 GWWAG--------KVNNKVGIF--------------------PSNYVSFKPSGYGKSGVVAPPVV 103

  Fly  1024 SIQELIMHQYHSELPVTVKSGAILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLD 1088
            |                    |:..:||  |..|||     |.|.||.|.||.||:...:...
Zfish   104 S--------------------ALEPQPV--EFCELS-----LQEVIGVGGFGKVYRGTWRGEL-- 139

  Fly  1089 VAVKTCRMTLPDEQ----KRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTY 1149
            ||||..|.. |||.    .:....|.|:.....||||:.|.|:|:|:..:.::||...||:|
Zfish   140 VAVKAARQD-PDEDISVTAQNVQNEARLFAMLQHPNIISLKGVCLQEPNLCLIMEYASGGAL--- 200

  Fly  1150 LRKNSNGLTTRQ-----QMGMCRDAAAGMRYLESK---NCIHRDLAARNCLV-------DLE-HS 1198
                |..|..|:     .:......|.||.||.|:   ..|||||.:.|.|:       .:| .:
Zfish   201 ----SRALAGRRIPPHVLVNWAVQIARGMLYLHSEAIVPVIHRDLKSNNILLAEPIEKGSIEGKT 261

  Fly  1199 VKISDFGMSRE--EEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPY 1261
            :||:|||::||  :...:.:.|    ...|.|||.:....::...||||||:|:||:.: |:.||
Zfish   262 LKITDFGLAREWHKTTKMSTAG----TYAWMAPEVIKSSTFSKGSDVWSYGVLLWELLT-GEAPY 321

  Fly  1262 SGMTNSRARERIDTGY-------RMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDAL 1317
            .|:      :.:...|       .:|.|.:.||...:||.:||..|...||.|..|...:.||
Zfish   322 RGI------DGLAVAYGVAVNKLTLPIPSTCPEPFAQLMSECWDQDPHRRPSFGCILEQLTAL 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	11/85 (13%)
		TyrKc	1063..1311	CDD:197581	87/276 (32%)
		PTKc_Fes_like	1067..1315	CDD:270637	87/276 (32%)
LOC101886393	XP_005172193.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900