DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and si:ch73-40a2.1

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	XP_009301289.1	Gene:	si:ch73-40a2.1 / 101885322	ZFINID:	ZDB-GENE-160728-89	Length:	746	Species:	Danio rerio

Alignment Length:	344	Identity:	104/344 - (30%)
Similarity:	170/344 - (49%)	Gaps:	56/344 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1021 PFASIQELIMHQ--YHSELPVT----------------VKSGAILRRPVCRERWELSNDDVVLLE 1067
            |.|.|:|...:.  |....|.|                :|...:..|.|..||.:|.     |.:
Zfish   355 PTAQIEEASQYDCAYEPMRPHTLQLKSTMSDSDQMLDGIKDHLLCLRDVLVERTKLQ-----LSQ 414

  Fly  1068 RIGRGNFGDVYKAKLKSTKLD----VAVKTCRMTL-PDEQKRKFLQEGRILKQYDHPNIVKLIGI 1127
            ::|:|.||.||:. :.|.|:.    |||||.:..: .:|....||:|..::|.:||.|:|||:|:
Zfish   415 KLGKGEFGAVYEG-IFSPKIGQDIRVAVKTSKDVIHSEEDLESFLKEAEMMKHFDHVNVVKLLGV 478

  Fly  1128 CVQKQP------IMIVMELVLGGSLLTYLRKNSNGLTTRQQ-----------MGMCRDAAAGMRY 1175
            .::..|      .::::..:....|.::||      .||..           :....|.||||.|
Zfish   479 ALEWDPESSMVVPLVILPYMKHRDLHSFLR------ATRYDDVPMFVPHQSLLRFMMDIAAGMEY 537

  Fly  1176 LESKNCIHRDLAARNCLVDLEHSVKISDFGMSR---EEEEYIVSDGMKQIPVKWTAPEALNFGKY 1237
            |..:..:|||||||||::..:..|.::|||:|:   ....|.......::||:|.|.|:::...:
Zfish   538 LSLQGFLHRDLAARNCMLGDDLRVCVADFGLSKMMYSSNYYRHKSQDVKLPVRWMAIESVSDFIF 602

  Fly  1238 TSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAE 1302
            |:..||||:|:.||||.|:|..||.|::|....:.::.|:|: :......::|.|||.||..|..
Zfish   603 TTKSDVWSFGVTMWEITSRGKVPYPGVSNYELLDYLEKGHRL-SQGDNDSKLYELMLSCWHRDPS 666

  Fly  1303 SRPHFDEIYNVVDALILRL 1321
            .||.|.|::..:.||:..|
Zfish   667 QRPSFGELHQSLSALLSEL 685

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	5/19 (26%)
		TyrKc	1063..1311	CDD:197581	88/272 (32%)
		PTKc_Fes_like	1067..1315	CDD:270637	87/272 (32%)
si:ch73-40a2.1	XP_009301289.1	EphR_LBD	42..185	CDD:295439
		STYKc	410..678	CDD:214568	89/280 (32%)
		PTKc	415..678	CDD:270623	87/270 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900