DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and sla2a

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	XP_009304328.1	Gene:	sla2a / 100536664	ZFINID:	ZDB-GENE-141216-296	Length:	254	Species:	Danio rerio

Alignment Length:	178	Identity:	36/178 - (20%)
Similarity:	64/178 - (35%)	Gaps:	64/178 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   925 SASDDVL-----SMKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLPREEVVRLL----NNDGDF 980
            |..||:|     |..:.|:...:..:.:         .::||...:.|....:||    |..|.|
Zfish    59 SEDDDMLRVCSTSTGNECFIPHTYVSKV---------HDQWFFEGISRRNAEQLLMLPQNYSGCF 114

  Fly   981 LVRE----------TIRNEESQI--VLSVCWNGHKHFIVQTTGEGNFRFE-GPPFASIQELIMH- 1031
            |:||          ::|....|:  ||        |:.:.....|.|..: ..||:::.:|:.:
Zfish   115 LIRESQSFPGLYSLSVRQHSGQMHTVL--------HYKIYQLHNGWFYIQPNHPFSTLSQLVDYY 171

  Fly  1032 ---------------QYHSELPVTVKSGAILRRPVCRER----W-ELS 1059
                           :.|..:|....|.:    ||..::    | |||
Zfish   172 SRSSVGSFCHLTEPCRLHDSIPTAAHSPS----PVAAQKSNFNWRELS 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	22/118 (19%)
		TyrKc	1063..1311	CDD:197581
		PTKc_Fes_like	1067..1315	CDD:270637
sla2a	XP_009304328.1	SH3	32..86	CDD:302595	6/26 (23%)
sla2a	XP_009304328.1	SH2	79..180	CDD:301589	21/117 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000