DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and txk

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	XP_003201292.4	Gene:	txk / 100534735	ZFINID:	ZDB-GENE-130530-553	Length:	509	Species:	Danio rerio

Alignment Length:	380	Identity:	136/380 - (35%)
Similarity:	209/380 - (55%)	Gaps:	42/380 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   959 EWFHGVLPREEVVRLL---NNDGDFLVRETIRNEESQIVLSV---CWNGH---KHFIVQTTGEGN 1014
            :|:...:.|.|...||   ..||.|:||.:  ::.|...:||   | :|.   :|:.::.|.|..
Zfish   130 DWYCKNINRAEAEHLLRQEGKDGGFVVRSS--SQPSTYTVSVYTHC-SGKGEVRHYQIKRTDEDK 191

  Fly  1015 FRF-EGPPFASIQELI-MHQYHSELPVTVKSGAI--LRRPV-----CR--------ERWELSNDD 1062
            |.. |...|.||.||| .|:|::       :|.:  ||.|:     |:        ::.|::..:
Zfish   192 FYLAENHVFISIPELINYHKYNA-------AGLVARLRYPIGPKGKCQPATAGFSSDKMEINPSE 249

  Fly  1063 VVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGI 1127
            :..::.:|.|.||.|...|.:: :..||:||.|....:|.  .|::|.:|:.:..||.:|:|.|:
Zfish   250 LTFMKELGSGQFGVVRLGKWRA-QHKVAIKTIREGAMNED--DFIEEAKIMTRLCHPKLVQLYGV 311

  Fly  1128 CVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCL 1192
            ||.::||.||.|.:..|.||.:||::|..|...|.:.||:|...||.|||....|||||||||||
Zfish   312 CVTQRPICIVTEFMENGCLLHFLRQHSKTLGRSQMLCMCQDVCEGMEYLEHNQFIHRDLAARNCL 376

  Fly  1193 VDLEHSVKISDFGMSRE--EEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFS 1255
            |:..:.||:.||||:|.  :.:|..|.| .:.||||:.||.|:|.|:::..||||:|:||||:||
Zfish   377 VNERNVVKVCDFGMTRYVLDNQYTSSMG-SRFPVKWSPPEVLHFNKFSNKSDVWSFGVLMWEVFS 440

  Fly  1256 KGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEI 1310
            :|.||:...||....|.:..|.|:..|......:|.:|.:||......||.|.|:
Zfish   441 EGKTPFDNRTNVEVVEEVTQGSRLYRPHLATPHIYNIMYRCWHERPHGRPAFSEL 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	28/90 (31%)
		TyrKc	1063..1311	CDD:197581	102/250 (41%)
		PTKc_Fes_like	1067..1315	CDD:270637	102/246 (41%)
txk	XP_003201292.4	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910