DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and ltk

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	XP_002933782.3	Gene:	ltk / 100498306	XenbaseID:	XB-GENE-22068681	Length:	1314	Species:	Xenopus tropicalis

Alignment Length:	321	Identity:	115/321 - (35%)
Similarity:	163/321 - (50%)	Gaps:	44/321 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly  1006 IVQTTGEGNFRFEGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCRERWELSNDDVVLLERIG 1070
            |:.|....|:.|.|.. ||:.||      .|:|                     ..::.||..:|
Frog   885 IIMTDYNPNYCFAGKG-ASLSEL------KEVP---------------------RKNITLLRALG 921

  Fly  1071 RGNFGDVYKAKL-----KSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQ 1130
            .|.||:||:..:     ....|.||:||......::.:..||.|..|:.::.|.|||:.||:.:|
Frog   922 HGAFGEVYEGMVVGISGDPNPLQVAIKTLPEICSEQDEMDFLMEALIISKFSHQNIVRCIGVSLQ 986

  Fly  1131 KQPIMIVMELVLGGSLLTYLRKN------SNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAAR 1189
            ..|..|::||:.||.:.::||:|      .:.|:....:.|.||.|.|.:|||..:.||||:|||
Frog   987 TLPRFILLELMSGGDMKSFLRQNRPWINQPSTLSMLDLLNMARDIACGCKYLEENHFIHRDIAAR 1051

  Fly  1190 NCLVDLEHS---VKISDFGMSRE--EEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGIL 1249
            |||:....:   .||.||||:|:  ...|....|...:||||..|||...|.:||..|.||:|:|
Frog  1052 NCLLTYSGTGRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFLEGVFTSKTDTWSFGVL 1116

  Fly  1250 MWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEI 1310
            :|||||.|..||...||....|.:.:|.||..||:.|..:||:|.|||....|.||:|..|
Frog  1117 LWEIFSLGYMPYPCKTNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHTPEHRPNFSTI 1177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	10/32 (31%)
		TyrKc	1063..1311	CDD:197581	104/264 (39%)
		PTKc_Fes_like	1067..1315	CDD:270637	102/260 (39%)
ltk	XP_002933782.3	LDLa	230..263	CDD:197566
		MAM	277..431	CDD:99706
		PTKc_ALK_LTK	907..1183	CDD:270632	106/292 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910