DRSC/TRiP Functional Genomics Resources

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Protein Alignment FER and tie1

DIOPT Version :9

Sequence 1:NP_524288.3 Gene:FER / 41118 FlyBaseID:FBgn0000723 Length:1325 Species:Drosophila melanogaster
Sequence 2:XP_002931650.3 Gene:tie1 / 100496664 XenbaseID:XB-GENE-922217 Length:1127 Species:Xenopus tropicalis


Alignment Length:316 Identity:120/316 - (37%)
Similarity:167/316 - (52%) Gaps:41/316 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly  1033 YHSELPVTVKSGA--------------ILRRPVCRERWE------LSNDDVVLLERIGRGNFGDV 1077
            :|.....|.:||:              :.|||  |.:.|      |..:|:...:.||.||||.|
 Frog   781 FHRRRMFTYQSGSGEETILQFSSGTLTLSRRP--RPQTEPFSYPVLEWEDIKFEDVIGEGNFGQV 843

  Fly  1078 YKAKLK--STKLDVAVKTCRMTLPDEQKRKFLQEGRIL-KQYDHPNIVKLIGICVQKQPIMIVME 1139
            .||.:|  ..|::.|:|..:....:...|.|..|..:| |...||||:.|:|.|..:..:.|.:|
 Frog   844 IKAMIKKDGQKMNAAIKMLKEFASENDHRDFAGELEVLCKLGHHPNIINLLGACENRGYLYIAIE 908

  Fly  1140 LVLGGSLLTYLRKN---------------SNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAAR 1189
            ....|:||.:|||:               ::.||::|.:....|.|.||:||..|..||||||||
 Frog   909 YAPYGNLLDFLRKSRVLETDPVFAKEHGTASTLTSQQLLQFASDVAKGMQYLSEKQFIHRDLAAR 973

  Fly  1190 NCLVDLEHSVKISDFGMSREEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIF 1254
            |.||......||:|||:||.||.| |...|.::||:|.|.|:||:..||:..||||:|:|:|||.
 Frog   974 NVLVGENLVTKIADFGLSRGEEVY-VKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIV 1037

  Fly  1255 SKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEI 1310
            |.|.|||.|||.:...|.:..||||..|::..:|:|.||.|||......||.|.:|
 Frog  1038 SLGGTPYCGMTCAELYENLPQGYRMEKPRNCDDEVYELMRQCWRDRPYERPPFSQI 1093

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FERNP_524288.3 F-BAR_Fes_Fer 7..243 CDD:153341
SH2_Fps_family 953..1039 CDD:198224 1/5 (20%)
TyrKc 1063..1311 CDD:197581 109/266 (41%)
PTKc_Fes_like 1067..1315 CDD:270637 109/262 (42%)
tie1XP_002931650.3 IG_like 124..203 CDD:214653
EGF_CA <222..247 CDD:238011
EGF_CA 306..336 CDD:238011
Ig 341..432 CDD:416386
Ig strand A 341..345 CDD:409353
Ig strand A' 351..355 CDD:409353
Ig strand B 358..367 CDD:409353
Ig strand C 375..380 CDD:409353
Ig strand C' 384..386 CDD:409353
Ig strand D 390..394 CDD:409353
Ig strand E 397..405 CDD:409353
Ig strand F 413..421 CDD:409353
Ig strand G 424..432 CDD:409353
fn3 448..511 CDD:394996
FN3 633..724 CDD:238020
PTKc_Tie1 826..1122 CDD:270671 110/269 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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