DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and erbb4

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	XP_031748752.1	Gene:	erbb4 / 100493234	XenbaseID:	XB-GENE-877077	Length:	1300	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	91/261 - (34%)
Similarity:	153/261 - (58%)	Gaps:	11/261 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly  1058 LSNDDVVLLERIGRGNFGDVYKA----KLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDH 1118
            |...::..::.:|.|.||.|||.    :.::.|:.||:|....|...:...:|:.|..|:...||
Frog   704 LKETELKRIKILGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANAEFMDEALIMASMDH 768

  Fly  1119 PNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIH 1183
            |::|:|:|:.: ...|.:|.:|:..|.||.|:.::.:.:.::..:..|...|.||.|||.:..:|
Frog   769 PHLVRLLGVSL-SPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVH 832

  Fly  1184 RDLAARNCLVDLEHSVKISDFGMSR----EEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVW 1244
            |||||||.||...:.|||:|||::|    :|:||....|  ::|:||.|.|.:::.|:|...|||
Frog   833 RDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGG--KMPIKWMALECIHYRKFTHQSDVW 895

  Fly  1245 SYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDE 1309
            |||:.:||:.:.|..||.|:......:.::.|.|:|.|.....::|.:|::||..||:|||.|.|
Frog   896 SYGVTVWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPVCTIDVYMVMVKCWMIDADSRPKFKE 960

  Fly  1310 I 1310
            :
Frog   961 L 961

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	90/256 (35%)
		PTKc_Fes_like	1067..1315	CDD:270637	90/252 (36%)
erbb4	XP_031748752.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910