DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FER and lmtk2

DIOPT Version :9

Sequence 1:	NP_524288.3	Gene:	FER / 41118	FlyBaseID:	FBgn0000723	Length:	1325	Species:	Drosophila melanogaster
Sequence 2:	XP_002932018.3	Gene:	lmtk2 / 100489240	XenbaseID:	XB-GENE-980913	Length:	1419	Species:	Xenopus tropicalis

Alignment Length:	285	Identity:	81/285 - (28%)
Similarity:	144/285 - (50%)	Gaps:	25/285 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly  1055 RWELSNDDVVLLERIGRGNFGDVYKAKL--KSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYD 1117
            ::::....:..::.||.|.||.|...::  :::...|.||..:.:...:::..|:..|.......
Frog   126 KYQIPRHSLSYIQEIGNGWFGKVLLGEIYRENSVARVIVKELKASANPKEQDHFINHGEPYSFLH 190

  Fly  1118 HPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLR------KNSNGLTTRQQMGMCRDAAAGMRYL 1176
            |||||:.:|.|::..|.::|.||...|.|.|||.      |....:...|:|. |: .|||:..:
Frog   191 HPNIVQCVGHCIETMPYLLVFELCDLGDLKTYLTNQREKLKGDTEIVLLQRMA-CQ-IAAGLAIM 253

  Fly  1177 ESKNCIHRDLAARNCLVDLEHSVKISDFGM--SREEEEYIVSDGMKQIPVKWTAPE-------AL 1232
            ...|.:|.|||.|||.|..:.:|||.|:|:  :|.:|:|:.:...|.|||:|||||       .|
Frog   254 HKHNFVHSDLALRNCYVTSDLTVKIGDYGIGFTRYKEDYMETTEEKFIPVRWTAPELVTSYQDQL 318

  Fly  1233 NFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERI--DTGYRMPTPK-STP--EEMYRL 1292
            .....|...::||.|:.:||:|....|||..:::|....::  ....::|.|: ..|  :..|.:
Frog   319 LVADQTKSSNIWSLGVTLWELFENAATPYEDLSDSEVLAQVIKQREVKLPNPQLEQPYADRWYEV 383

  Fly  1293 MLQCWAADAESRPHFDEIYNVVDAL 1317
            :..||.. ::.|...:|::.::..|
Frog   384 LQFCWLT-SDKRLTAEEVHRLLTYL 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224
		TyrKc	1063..1311	CDD:197581	80/269 (30%)
		PTKc_Fes_like	1067..1315	CDD:270637	80/269 (30%)
lmtk2	XP_002932018.3	PTKc_Aatyk2	136..406	CDD:270669	80/272 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910