Protein Alignment FER and si:ch73-340m8.2

DIOPT Version :10

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: XP_002665190.3
• Gene: si:ch73-340m8.2 / 100332982
• ZFINID: ZDB-GENE-110411-209
• Length: 480
• Species: Danio rerio
• Alignment Length: 487
• Identity: 146/487 - (29%)
• Similarity: 223/487 - (45%)
• Gaps: 63/487 - (12%)

  Fly   877 CNCPPAGQKPVKP-----SVQISGHKDHPFESSSG---------ELDENSDRDIDNDEE------ 921
            |.|.|....|..|     ..|.|.::|..:.|...         .|.:....::..:.|
Zfish     4 CECKPKCCCPCCPCCLTKDQQASVNRDRVYTSIYSYPSRTIWDLNLRKGDILEVTGETEYWLYVR 68

  Fly   922 EEDSASDDVLS-MKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLPREEVVRLL----NNDGDFL 981
            ...:.:|...| :::|.|........:......|.|    |..|..|.|..|.|    |.:|.||
Zfish    69 RRTAKTDKSKSFIEEHGYVPKDFVKPLDSVEAEPWY----FENVKTRVEAKRCLLRPENKEGAFL 129

  Fly   982 VRETIRNEESQIVLSVCWNGH-KHFIVQTTGEGNFRF---EGPPFASIQELIMHQYHSE----LP 1038
            |.:.  :|.:...|||....| :|:.:: .||.:.:|   ....|.|:::||  :::|:    |.
Zfish   130 VWKC--DENNHYYLSVKNGPHARHYRIK-QGENDQQFFLVHHTTFQSLRKLI--EFYSKHEGGLC 189

  Fly  1039 VTVKSGAI-LRRPVCR-----ERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCR-M 1096
            ..:....: |.:||.:     .:.|:....:...:::|.|.|.||::....:| .:||:|..: :
Zfish   190 AKLHEACVKLDQPVPQTLSFDSKCEIDRSSLTKQQKLGSGEFADVWQGLWNNT-TEVAIKEFKGV 253

  Fly  1097 TLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYL--RKNSNGLTT 1159
            ...|.|     .|..|:|...|..::||..:|...||:.||.||:..|||.|:|  .|....|..
Zfish   254 NYSDIQ-----TEIEIMKDLHHERLLKLYAVCTTSQPMCIVTELMKNGSLKTFLLRHKEKQDLEF 313

  Fly  1160 RQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGM---SREEEEYIVSDGMKQ 1221
            ...:........||.|:|:| .:||||.|.|.|:....|.||:|||:   :|...:.|.||  .:
Zfish   314 SLMLDFAIQITEGMIYIENK-IVHRDLRAENILLTEMQSCKIADFGLAQVNRPGNQRISSD--VR 375

  Fly  1222 IPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTP 1286
            :||||.|||..:.|:|||..||||:|||:.||.:.||.||.|.........|..|.|||.|...|
Zfish   376 LPVKWMAPEIFDNGEYTSKSDVWSFGILLTEIVTYGDDPYPGQDKMSCVRGIQRGERMPRPAGCP 440

  Fly  1287 EEMYRLMLQCWAADAESRPHFDEIYNVVDALI 1318
            |.:|.:||.||.|:.:.||.|.|:..::.|||
Zfish   441 ESLYGIMLLCWKANPKERPTFTELREMLMALI 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	28/97 (29%)
		PTKc_Fes_like	1067..1315	CDD:270637	96/253 (38%)
si:ch73-340m8.2	XP_002665190.3	SH2	99..192	CDD:472789	28/101 (28%)
		Protein Kinases, catalytic domain	225..468	CDD:473864	96/251 (38%)