Protein Alignment FER and met

DIOPT Version :9

• Sequence 1: NP_524288.3
• Gene: FER / 41118
• FlyBaseID: FBgn0000723
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_001007125.1
• Gene: met / 100150664
• ZFINID: ZDB-GENE-041014-1
• Length: 1382
• Species: Danio rerio
• Alignment Length: 583
• Identity: 149/583 - (25%)
• Similarity: 255/583 - (43%)
• Gaps: 133/583 - (22%)

  Fly   797 TTTPSKENSRLKFKVPKIQKKSKAIRNTFRSKLLNFQLKRSKPCK---------QCTKRRRIHPS 852
            |.||..:.:.|:.|||.:.:  :|::|....::.|      :.|:         :||....:..:
Zfish   846 TVTPRGKKNILEIKVPPVNQ--EAVKNGEVLRVSN------RTCESVTLVGNTLECTVPMELQTA 902

  Fly   853 KSVFDFAKEFEVEQPAGSAADEQFCNCPPAGQKPVKPSVQISGHKDHPFESSSGELDENSDRDID 917
                  |||.|||....:::             .:...|.::..:|:....:.|
Zfish   903 ------AKELEVEWKQATSS-------------VILGRVILAQDQDYRILITGG----------- 937

  Fly   918 NDEEEEDSASDDVLSMKDHCYCVP---SLAASISLSTNRPLYEEE------WFHG---------- 963
                                .||.   .|..::.:...|..:.::      |:.|
Zfish   938 --------------------VCVSILLLLLIAVFVWIKRKKHIDDLAKTMVWYDGRAHIPHLDML 982

  Fly   964 -----VLPREEVVRLLNNDGDFLVRETIRNEESQIVLSVCWNGHKHFIVQT---------TGEGN 1014
                 |.|.:|:|.  :...|:  |.|:. |:..:.||...:...|....:         ..||:
Zfish   983 ANARSVSPTDEMVS--HESVDY--RTTLL-EDQNLPLSQTESCRPHLYAHSHVDLSPMLGPMEGD 1042

  Fly  1015 FRFEGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCRERWELSNDDVVL--LERIGRGNFGDV 1077
              ...|...|...:.:...|.||.. |:...|.|            :|::|  .|.||||:||.|
Zfish  1043 --LASPLLPSTAPIDLGSLHPELLKXVQHVVIAR------------EDLLLHVNEIIGRGHFGCV 1093

  Fly  1078 YKAKL---KSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQ--PIMIV 1137
            :...|   ...|...|:|:.......|:..:||:||.|:|.:.|||::.|:|||:..:  | ::|
Zfish  1094 FHGTLLEPDGQKQHCAIKSLNRITDIEEVSQFLKEGIIVKDFSHPNVLSLLGICLPSEGSP-LVV 1157

  Fly  1138 MELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKIS 1202
            :..:..|.|..::|..|:..|.:..||.....|.||.||.||..:|||||||||::|..::||::
Zfish  1158 LPYMKHGDLRNFIRDESHNPTVKDLMGFGLQVAKGMEYLASKKFVHRDLAARNCMLDESYTVKVA 1222

  Fly  1203 DFGMSR---EEEEYIVSD--GMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYS 1262
            |.|::|   ::|.|.|.:  |:| :||||.|.|:|...|:|:..||||:|:|:||:.::|..|||
Zfish  1223 DVGLARDVYDKEYYSVHNKHGVK-LPVKWMALESLQTHKFTTKSDVWSFGVLLWELMTRGAPPYS 1286

  Fly  1263 GMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDALILRLDNSH 1325
            .:.:......:..|.|:..|:..|:.:|.:|::||....|.||.|.|:.:.:.|:.......|
Zfish  1287 DVNSFDITVFLLQGRRLLQPEFCPDALYNVMIECWHPKPERRPTFLELVSRISAIFSSFSGEH 1349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	NP_524288.3	F-BAR_Fes_Fer	7..243	CDD:153341
		SH2_Fps_family	953..1039	CDD:198224	21/115 (18%)
		TyrKc	1063..1311	CDD:197581	97/259 (37%)
		PTKc_Fes_like	1067..1315	CDD:270637	96/257 (37%)
met	NP_001007125.1	Sema_MET_like	43..511	CDD:200509
		PSI	514..559	CDD:214655
		IPT	562..653	CDD:301692
		IPT_plexin_repeat2	654..736	CDD:238584
		IPT	740..823	CDD:301692
		Pkinase_Tyr	1079..1338	CDD:285015	97/260 (37%)
		PTKc_Met_Ron	1083..1344	CDD:270649	97/262 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100013
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900