DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Aduk and AT3G61960

DIOPT Version :9

Sequence 1:	NP_731331.1	Gene:	Aduk / 41112	FlyBaseID:	FBgn0037679	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_567122.1	Gene:	AT3G61960 / 825369	AraportID:	AT3G61960	Length:	626	Species:	Arabidopsis thaliana

Alignment Length:	606	Identity:	149/606 - (24%)
Similarity:	269/606 - (44%)	Gaps:	120/606 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITDFEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSRENLITEIRLLRELKHKYIVT 70
            :.|:.:..::|:||:|.|:.|:|:......|:|.::...||...|:||:.||.:|..:.|..|:.
plant     7 VGDYALGPRIGSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPKVRDNLLKEISILSTIDHPNIIR 71

  Fly    71 LQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKALPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQ 135
            ..:.......|::|||||:.|:|:.:|.....:||:..::|:||||..:|.::.....|.|||||
plant    72 FYEAIETGDRIFLVLEYCSGGDLAGYINRHGKVPEAVAKHFMRQLALGLQVLQEKHFIHRDLKPQ 136

  Fly   136 NLLLTRGANNVSLKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYDAKADLWSIGVILYE 200
            ||||:.......||:.|||||:.|....:.:...||||||||||:|..:|||||||||.|.||::
plant   137 NLLLSSKEVTPLLKIGDFGFARSLTPESMAETFCGSPLYMAPEIIRNQKYDAKADLWSAGAILFQ 201

  Fly   201 CLFGKAPYSSRTIEELLLRIRKAEAITLPPNAR--ISNECHDLLRRLLAHEPTARISFADFFAHP 263
            .:.||.|:......:|...|.:...:..|.:.|  |..:|.||.|.||...|..|::|.:||.|.
plant   202 LVTGKPPFDGNNHIQLFHNIVRDTELKFPEDTRNEIHPDCVDLCRSLLRRNPIERLTFREFFNHM 266

  Fly   264 FL-DLKTFP-TEH---TLQKAIDLVTQACAYDEKHNYK---EAYYLYCSALQYFVPLITEETDAT 320
            || :.:..| .||   :......|:..|......:.:|   |..:.:.|:          .:.:.
plant   267 FLREPRQIPDVEHSGFSTCTGKSLLPSAQPSTSTNRFKSSAENVHKHGSS----------SSASN 321

  Fly   321 KRLALRNRALSYTKRAEEIKNC------------IIEDEYRM----------------------- 350
            .::::.:.:...|::..| ..|            :||.||.:
plant   322 SQISMPHTSFEKTRKDTE-GQCSSNQSGVVDSLELIEREYVLVNRPSASLEGSSDCFDTSLQDSG 385

  Fly   351 ---LAERQRQAATAATANQEPSSATQVPAAQPSSSRVAE-----MLEPDSRYKQLYALSNSSPSM 407
               :..|..:.::::...|:|.|....|.....|..:.|     ::.|.::.:.|:..:.:...:
plant   386 FPNILPRNEKVSSSSLEAQKPLSDVSGPRPASVSYLLTEVQRLTIVHPPTKLQLLHQYAQALTEL 450

  Fly   408 KTGLEIGRKGE-----------LYLYERKLDAALESYTSALG-------------ILVPFVNNEP 448
            .:  |:|..|:           |.::.:.|:.. :|:..::|             ..:|.:|:
plant   451 AS--EMGNTGQVKESFAVTLVVLAVWRKALEIC-DSWMMSVGENEVNPDPTTAPETSIPDLNS-- 510

  Fly   449 KGERRNLLLQQLEFWMKEAESIKSIL----SAKHLDD-----------------EEQKLSTRTSL 492
            ....:..:.|:....:.:||::.:.|    :|.|:.|                 .|:.||.:.|.
plant   511 PAPAKTWVTQEFVTALNQAENLSTQLNETSAATHMPDAMETIYERALAYGKSGGAEEYLSNKESA 575

  Fly   493 RTITFQGWSKPPLIFFILFIV 513
            .|:    :.|  .|..:.||:
plant   576 ATL----YKK--AILLLSFII 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aduk	NP_731331.1	S_TKc	9..265	CDD:214567	97/257 (38%)
		PKc_like	13..264	CDD:304357	97/252 (38%)
		MIT_2	274..348	CDD:239147	11/91 (12%)
		MIT	407..472	CDD:282117	12/88 (14%)
AT3G61960	NP_567122.1	S_TKc	10..268	CDD:214567	97/257 (38%)
AT3G61960	NP_567122.1	STKc_ATG1_ULK_like	16..267	CDD:270911	97/250 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	222	1.000	Domainoid score	I706
eggNOG	1	0.900	-	-		E1_KOG0595
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003680
OrthoInspector	1	1.000	-	-		otm3171
orthoMCL	1	0.900	-	-		OOG6_101938
Panther	1	1.100	-	-	O	PTHR24348
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.810