DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Aduk and AT3G53930

DIOPT Version :9

Sequence 1:	NP_731331.1	Gene:	Aduk / 41112	FlyBaseID:	FBgn0037679	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001078281.1	Gene:	AT3G53930 / 824560	AraportID:	AT3G53930	Length:	712	Species:	Arabidopsis thaliana

Alignment Length:	486	Identity:	153/486 - (31%)
Similarity:	247/486 - (50%)	Gaps:	77/486 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITDFEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSRENLITEIRLLRELKHKYIVT 70
            |.|:.:..::|:||::.|::.||....|..|||.:.|:.|::..:|:|::||.:||::.|..|:.
plant    17 IGDYAVGRQIGSGSFSVVWEGRHLVHGTVVAIKEIAMARLNKKLQESLMSEIIILRKINHPNIIR 81

  Fly    71 LQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKALPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQ 135
            ..|.......|.:|||||..|:||.:|....::||:|.::|:.||||.:|.:|.|::.|.|||||
plant    82 FIDMIEAPGKINLVLEYCKGGDLSMYIHKHGSVPEATAKHFMLQLAAGLQVLRDNNIIHRDLKPQ 146

  Fly   136 NLLLTRGANNVSLKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYDAKADLWSIGVILYE 200
            ||||:...|:.:||:||||||:.|:...:.:.|.||||||||||::..:|||||||||:|.||::
plant   147 NLLLSTDDNDAALKIADFGFARSLQPRGLAETLCGSPLYMAPEIMQLQKYDAKADLWSVGAILFQ 211

  Fly   201 CLFGKAPYSSRTIEELLLRIRKAEAITLPPNAR-ISNECHDLLRRLLAHEPTARISFADFFAHPF 264
            .:.|:.|::..:..:||..|.::..:..|.:.| :|.:|.||.::||...|..|::|.:||.|||
plant   212 LVTGRTPFTGNSQIQLLQNIIRSTELHFPADCRDLSTDCKDLCQKLLRRNPVERLTFEEFFHHPF 276

  Fly   265 -------------LDLKTFPTEHTL----QKAIDLVTQACA----YDEKHNYKEAYYLYCSALQY 308
                         ||.:|....|:.    .:.|:.::|...    .|:..:..|.   ..|:.::
plant   277 LSDKQSYDFTRSRLDSRTMNDFHSSGSSPSRNIEEISQEDGLPFFLDDDSSGPEG---SPSSFKH 338

  Fly   309 FVPLITEETDATKRLALRNRALSYTKRAEEIKNCIIEDEYRMLAERQRQAATAATAN-----QEP 368
            ..|:.:....:.:|   |..|||      .:||..:...|..::.|      |.|.|     ...
plant   339 TSPMKSSYGFSVER---REAALS------PLKNMDLSSRYSRVSHR------AETNNFKFEGHRL 388

  Fly   369 SSATQV-PAAQPSS------SRVAEMLEPDSRYKQLYALSNSSPSMKTGLEIGRKGELYLYERKL 426
            |..:|. |::.|.|      .||.:  .||| ..|.|.|.:..|                    :
plant   389 SDRSQFKPSSLPDSRSFSTQGRVGD--SPDS-MDQDYVLISGPP--------------------V 430

  Fly   427 DAALESYTSALGILVPFVNNEPKGE--RRNL 455
            |....|..|......||.::.|..|  :||:
plant   431 DIPSSSSGSPKPFNYPFKSHSPPVEFIKRNV 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aduk	NP_731331.1	S_TKc	9..265	CDD:214567	106/269 (39%)
		PKc_like	13..264	CDD:304357	104/251 (41%)
		MIT_2	274..348	CDD:239147	14/81 (17%)
		MIT	407..472	CDD:282117	9/51 (18%)
AT3G53930	NP_001078281.1	STKc_ATG1_ULK_like	26..276	CDD:270911	104/249 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	222	1.000	Domainoid score	I706
eggNOG	1	0.900	-	-		E1_KOG0595
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003680
OrthoInspector	1	1.000	-	-		otm3171
orthoMCL	1	0.900	-	-		OOG6_101938
Panther	1	1.100	-	-	O	PTHR24348
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.810