Protein Alignment Aduk and Ulk3

DIOPT Version :10

• Sequence 1: NP_731331.1
• Gene: Aduk / 41112
• FlyBaseID: FBgn0037679
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_082171.1
• Gene: Ulk3 / 71742
• MGIID: 1918992
• Length: 472
• Species: Mus musculus
• Alignment Length: 499
• Identity: 204/499 - (40%)
• Similarity: 293/499 - (58%)
• Gaps: 48/499 - (9%)

  Fly     3 LPRITDFEILEKLGAGSYATVYKARHKKQ-RTYHAIKYVEMSTLSQTSRENLITEIRLLRELKHK 66
            |||:..|.:.|:||:|:|||||||..||. |...|||.|...:|::.|.|||:|||.:|:.::|.
Mouse     8 LPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHP 72

  Fly    67 YIVTLQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKALPESTCRYFLRQLAAAVQYMRANDVSHFD 131
            :||.|:||.||:.|||:::|:|..|:||.||.|::.|||...|.|::|||:|:|::...::||.|
Mouse    73 HIVQLKDFQWDNDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLD 137

  Fly   132 LKPQNLLLTRGANNVSLKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYDAKADLWSIGV 196
            |||||:||: ......||:||||||||:...:....|:|||||||||:|.:.||||:.||||:||
Mouse   138 LKPQNILLS-SLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCRRQYDARVDLWSVGV 201

  Fly   197 ILYECLFGKAPYSSRTIEELLLRIRKAEAITLPPNARISNECHDLLRRLLAHEPTARISFADFFA 261
            ||||.|||:.|::||:..||..:||....|.||...::|.:|.|||:|||..:|..||||.||||
Mouse   202 ILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPQLSLDCRDLLQRLLERDPARRISFKDFFA 266

  Fly   262 HPFLDLKTFPTEHTLQKAIDLVTQACAYDEKHNYKEAYYLYCSALQYFVPLITEETDATKRLALR 326
            ||::||:..|:..:|.:|..||.:|...|::.:...|..|||.||.:|||.:..|.||.::.|::
Mouse   267 HPWVDLEHMPSGESLAQARALVVEAVKKDQEGDAAAALSLYCKALDFFVPALHYEVDAQRKEAIK 331

  Fly   327 NRALSYTKRAEEIKNCIIEDEYRMLAERQRQAATAATANQEPSSATQVPAAQPSSSRVAEMLEPD 391
            .:...|..||||:|..:......:|    ||..|                       |.|:|...
Mouse   332 AKVGQYVSRAEELKAIVSSSNQALL----RQGTT-----------------------VQELLREM 369

  Fly   392 SRYKQ--LYALSNSSPSMKTGLEIGRKGELYLYERKLDAALESYTSALGILVPFVNNEPKGERRN 454
            :|.|.  |.||..:|.::....|.|::.:          ||:.|..:||.|:..:..|..|.||.
Mouse   370 ARDKPRLLAALEVASAALAKEEEAGKEQD----------ALDLYQHSLGELLVLLAAEAPGRRRE 424

  Fly   455 LLLQQLEFWMKEAESIK-------SILSAKHLDDEEQKLSTRTS 491
            ||..:::..|..||.:|       |...|:.||.|....|.|:|
Mouse   425 LLHTEVQNLMARAEYLKEQIKIRESHWEAESLDKEGLSESVRSS 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aduk	NP_731331.1	Protein Kinases, catalytic domain	13..264	CDD:473864	132/251 (53%)
		MIT_2	274..348	CDD:239147	25/73 (34%)
		MIT	410..472	CDD:461228	18/68 (26%)
Ulk3	NP_082171.1	STKc_ULK3	18..269	CDD:271023	132/251 (53%)
		MIT_2	279..353	CDD:239147	25/73 (34%)
		MIT	374..449	CDD:239121	22/84 (26%)