DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aduk and pdik1l

DIOPT Version :9

Sequence 1:	NP_731331.1	Gene:	Aduk / 41112	FlyBaseID:	FBgn0037679	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001032789.2	Gene:	pdik1l / 569665	ZFINID:	ZDB-GENE-051113-236	Length:	341	Species:	Danio rerio

Alignment Length:	326	Identity:	75/326 - (23%)
Similarity:	135/326 - (41%)	Gaps:	95/326 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSRENLITEIRLLREL-----KHKYI 68
            :|:::::|.|||..||:|..::.....|:|.:...     |.||:...:|....|     :|..:
Zfish     8 YELIQEVGRGSYGVVYEAVVRQTGARVAVKKIRCH-----SPENVELALREFWALSSIQSQHPNV 67

  Fly    69 VTLQD-----------------------------------------FFWDDKNIYIVLEYCNAGN 92
            :.|::                                         :.|      .|:::|:.|:
Zfish    68 IHLEECVLQRDALAQRMSHGSSSSLYLELVETSLKGEITFDPCCAYYMW------FVMDFCDGGD 126

  Fly    93 LSAFIRTKKALPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLTR-----GANNVSLKVAD 152
            ::|::.::|. ...|...|:.||.:|:.::..|.:.|.||||.|:|:::     |:...:|||||
Zfish   127 MNAYLLSRKP-SRKTNTSFMLQLGSALAFLHRNQIIHRDLKPDNILISQGRTPAGSPEPTLKVAD 190

  Fly   153 FGFAQHLKLGEINQQ------------LKGSPLYMAPEIVRKHQYDAKADLWSIGVILYEC---- 201
            ||.::......:|.:            ..|:..|||||:...| |.||||::::|||::..
Zfish   191 FGLSKVCSGSGLNPEEPASVNKCFLSTACGTDFYMAPEVWEGH-YTAKADIFALGVIIWAMVERI 254

  Fly   202 ----------LFGKAPYSSRTI---EELLLRIRKAEAITLPPNARISN-ECHDLLRRLLAHEPTA 252
                      |.|........|   .|.||...|.| :.:|...:..| ....|:|.:|:..|..
Zfish   255 TFVDVETQKELLGSYVQQGEDIVPLGEALLENPKME-LNIPARKKSMNASMKQLIREMLSANPQE 318

  Fly   253 R 253
            |
Zfish   319 R 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aduk	NP_731331.1	S_TKc	9..265	CDD:214567	75/326 (23%)
		PKc_like	13..264	CDD:304357	74/322 (23%)
		MIT_2	274..348	CDD:239147
		MIT	407..472	CDD:282117
pdik1l	NP_001032789.2	STKc_PDIK1L	7..331	CDD:270879	75/326 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0595
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900