DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aduk and Ulk1

DIOPT Version :9

Sequence 1:	NP_731331.1	Gene:	Aduk / 41112	FlyBaseID:	FBgn0037679	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_006249627.1	Gene:	Ulk1 / 360827	RGDID:	1589743	Length:	1057	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	112/270 - (41%)
Similarity:	166/270 - (61%)	Gaps:	10/270 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FEILEK--LGAGSYATVYKARHKKQRTYH-AIKYVEMSTLSQTSRENLITEIRLLRELKHKYIVT 70
            ||...|  :|.|::|.|:|.||:::.... |:|.:....|:: |:..|..||::|:||||:.||.
  Rat    14 FEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAK-SQTLLGKEIKILKELKHENIVA 77

  Fly    71 LQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKALPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQ 135
            |.||.....::|:|:||||.|:|:.::.|.:.|.|.|.|.||:|:|.|:|.:.:..:.|.|||||
  Rat    78 LYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQQIAGAMQLLHSKGIIHRDLKPQ 142

  Fly   136 NLLLT----RGAN--NVSLKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYDAKADLWSI 194
            |:||:    |.||  |:.:|:||||||::|:...:...|.|||:|||||::....||.|||||||
  Rat   143 NILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSI 207

  Fly   195 GVILYECLFGKAPYSSRTIEELLLRIRKAEAITLPPNARISNECHDLLRRLLAHEPTARISFADF 259
            |.|:|:||.||||:.:.:.::|.|...|.:.:........|.....||..||......|:.|.:|
  Rat   208 GTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPAIPRETSAPLRQLLLALLQRNHKDRMDFDEF 272

  Fly   260 FAHPFLDLKT 269
            |.|||||..|
  Rat   273 FHHPFLDAST 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aduk	NP_731331.1	S_TKc	9..265	CDD:214567	108/264 (41%)
		PKc_like	13..264	CDD:304357	105/259 (41%)
		MIT_2	274..348	CDD:239147
		MIT	407..472	CDD:282117
Ulk1	XP_006249627.1	STKc_ULK1	13..279	CDD:271104	109/265 (41%)
		S_TKc	16..278	CDD:214567	106/262 (40%)
		DUF3543	844..1051	CDD:288883
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0595
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1084750at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820