Protein Alignment Aduk and Pdik1l

DIOPT Version :10

• Sequence 1: NP_731331.1
• Gene: Aduk / 41112
• FlyBaseID: FBgn0037679
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_666268.1
• Gene: Pdik1l / 230809
• MGIID: 2385213
• Length: 341
• Species: Mus musculus
• Alignment Length: 331
• Identity: 74/331 - (22%)
• Similarity: 143/331 - (43%)
• Gaps: 83/331 - (25%)

  Fly     9 FEILEKLGAGSYATVYKARHKKQRTYHAIKYV-------------EMSTLSQTS---------RE 51
            ::::.::|.|||..||:|..:|.....|:|.:             |...||...         .|
Mouse     8 YDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSIKSQHPNVIHLEE 72

  Fly    52 NLITEIRLLRELKH-----KYIVTLQ-----DFFWDDKNIY---IVLEYCNAGNLSAFIRTKKAL 103
            .::.:..:::::.|     .|:..::     :..:|.::.|   .|:::|:.|:::.::.::|.
Mouse    73 CILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKP- 136

  Fly   104 PESTCRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLTRGANNVS-----LKVADFGFAQHLKLGE 163
            ...|...|:.||::|:.::..|.:.|.||||.|:|:::...:.|     |||||||.::......
Mouse   137 NRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQSRMDTSDLEPTLKVADFGLSKVCSASG 201

  Fly   164 INQQ------------LKGSPLYMAPEIVRKHQYDAKADLWSIGVILYECLFGKAPYSSRTIEEL 216
            .|.:            ..|:..|||||:...| |.||||::::|:|::..|.......:.|.:||
Mouse   202 QNPEEPVSVNKCFLSTACGTDFYMAPEVWEGH-YTAKADIFALGIIIWAMLERITFIDTETKKEL 265

  Fly   217 -----------------LLRIRKAEAITLPPNARISNECHDLLRRLLAHEPTAR----------- 253
                             ||...|.|.:.......::.....|::.:||..|..|
Mouse   266 LGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSMNGRMKQLIKEMLAANPQDRPDAFELELRLV 330

  Fly   254 -ISFAD 258
             |:|.|
Mouse   331 QIAFKD 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aduk	NP_731331.1	Protein Kinases, catalytic domain	13..264	CDD:473864	74/327 (23%)
		MIT_2	274..348	CDD:239147
		MIT	410..472	CDD:461228
Pdik1l	NP_666268.1	STKc_PDIK1L	7..331	CDD:270879	71/324 (22%)