Protein Alignment Aduk and Aduk

DIOPT Version :10

• Sequence 1: NP_731331.1
• Gene: Aduk / 41112
• FlyBaseID: FBgn0037679
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_311054.5
• Gene: Aduk / 1272173
• VectorBaseID: AGAMI1_003026
• Length: 506
• Species: Anopheles gambiae
• Alignment Length: 498
• Identity: 227/498 - (45%)
• Similarity: 314/498 - (63%)
• Gaps: 19/498 - (3%)

  Fly     1 MSLPRITDFEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSRENLITEIRLLRELKH 65
            ||..:||::::||:||:|:||.||:|..|..:...|:|.:..|.||.|:.:|:|:||.||::|||
Mosquito     1 MSEAKITEYKLLERLGSGTYAIVYRAMKKTTKEILAVKVMAKSKLSCTAMDNIISEISLLKKLKH 65

  Fly    66 KYIVTLQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKALPESTCRYFLRQLAAAVQYMRANDVSHF 130
            ::||.::||.||::||||::|||:|||||::||..:.|.|.||:.||:|||.|::|||.:||||.
Mosquito    66 RHIVEMRDFLWDEENIYILMEYCDAGNLSSYIRQHRTLDEGTCKRFLQQLALALRYMRQHDVSHL 130

  Fly   131 DLKPQNLLLTRGANNVSLKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYDAKADLWSIG 195
            ||||.||||||.:....|||.||||||.|||.:.|..:|||||||||||:....|...|||||:|
Mosquito   131 DLKPANLLLTRASGTYVLKVGDFGFAQRLKLNQENTAVKGSPLYMAPEILLNSSYGPAADLWSVG 195

  Fly   196 VILYECLFGKAPYSSRTIEELLLRIRKAEAITLPPNARISNECHDLLRRLLAHEPTARISFADFF 260
            |||||||||:|||||.::.||..||.:.:.|.:|....||.:|..||..||..:|..||||..||
Mosquito   196 VILYECLFGRAPYSSTSLHELAERIHRNDPIAIPCRPPISTDCRQLLVSLLQRDPGRRISFEKFF 260

  Fly   261 AHPFLDLKTFPTEHTLQKAIDLVTQACAYDEKHNYKEAYYLYCSALQYFVPLITEETDATKRLAL 325
            ..|:|||.....|..|:|||.|:.:|...:::.....||..||..||||||:...|.||.||..|
Mosquito   261 DDPYLDLAHVACEENLEKAIALINRAIEMEQRQELAGAYRAYCQGLQYFVPITRAEPDAGKRQLL 325

  Fly   326 RNRALSYTKRAEEIKNCIIEDEYRMLAERQRQAATAATA--------------NQEPSSATQVPA 376
            |.|.|:|..|||.:|..|.....   .|||:|....||:              |...||:::...
Mosquito   326 RQRVLTYLNRAEALKQHIYATTQ---TERQQQQDVPATSVLKRPDEQGRSGAGNINSSSSSKEGT 387

  Fly   377 AQPSSSRVAEMLEPDSRYKQLYALSNSSPSMKTGLEIGRKGELYLYERKLDAALESYTSALGILV 441
            ......|.::.|...:....:..|:..:.::..|||||.:......|.||||||:||||||.:|:
Mosquito   388 GGGGGGRASDKLAEKAPEPGIAELARDNEAIARGLEIGWQAAKEASENKLDAALDSYTSALSLLI 452

  Fly   442 PFVNNE-PKGERRNLLLQQLEFWMKEAESIKSILSAKHLDDEE 483
            |.::.: |.|::| :|.|::..||:|||.||||.||:.:.:.|
Mosquito   453 PVLHQDIPAGQKR-VLRQRVVQWMEEAEQIKSIRSAQIMQEME 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aduk	NP_731331.1	Protein Kinases, catalytic domain	13..264	CDD:473864	137/250 (55%)
		MIT_2	274..348	CDD:239147	31/73 (42%)
		MIT	410..472	CDD:461228	31/62 (50%)
Aduk	XP_311054.5	STKc_ULK3	13..264	CDD:271023	137/250 (55%)
		MIT_2	274..345	CDD:239147	31/70 (44%)
		MIT	418..483	CDD:461228	31/65 (48%)