DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aduk and ulk2

DIOPT Version :9

Sequence 1:	NP_731331.1	Gene:	Aduk / 41112	FlyBaseID:	FBgn0037679	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_004911684.1	Gene:	ulk2 / 100487396	XenbaseID:	XB-GENE-6041491	Length:	1073	Species:	Xenopus tropicalis

Alignment Length:	270	Identity:	107/270 - (39%)
Similarity:	166/270 - (61%)	Gaps:	10/270 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITDFEILEK--LGAGSYATVYKARHKKQRTYH-AIKYVEMSTLSQTSRENLITEIRLLRELKHKY 67
            :.|||...|  :|.|::|.|:|.||:|:..:. |||.:....||: |:..|..||::|:||:|:.
Frog     4 VGDFEYSRKDLIGHGAFAVVFKGRHRKKTDWEVAIKSINKKNLSK-SQILLGKEIKILKELQHEN 67

  Fly    68 IVTLQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKALPESTCRYFLRQLAAAVQYMRANDVSHFDL 132
            ||.|.|......::::|:|:||.|:|:.:::.|..|.|.|.|.||:|:|||::.:.:..:.|.||
Frog    68 IVALYDVQEMPNSVFLVMEFCNGGDLADYLQAKGTLSEDTIRIFLQQIAAAMRVLHSKGIIHRDL 132

  Fly   133 KPQNLLLTRGA------NNVSLKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYDAKADL 191
            ||||:||:..:      :.:.:|:||||||::|:...:...|.|||:|||||::....|||||||
Frog   133 KPQNILLSYASRKKATFSGIRIKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDAKADL 197

  Fly   192 WSIGVILYECLFGKAPYSSRTIEELLLRIRKAEAITLPPNARISNECHDLLRRLLAHEPTARISF 256
            ||||.::|:||.||.|:.:.:.::|.|...|.:.:........|....|||..||......|:.|
Frog   198 WSIGTVIYQCLVGKPPFQANSPQDLRLFYEKNKNLVPSIPRETSAYLSDLLLALLQRNQKDRLDF 262

  Fly   257 ADFFAHPFLD 266
            ..||.|||||
Frog   263 EGFFNHPFLD 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aduk	NP_731331.1	S_TKc	9..265	CDD:214567	103/264 (39%)
		PKc_like	13..264	CDD:304357	100/259 (39%)
		MIT_2	274..348	CDD:239147
		MIT	407..472	CDD:282117
ulk2	XP_004911684.1	STKc_ULK2	2..272	CDD:271103	105/268 (39%)
ulk2	XP_004911684.1	DUF3543	881..1064	CDD:371876
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1084750at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010