DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aduk and ulk1

DIOPT Version :9

Sequence 1:	NP_731331.1	Gene:	Aduk / 41112	FlyBaseID:	FBgn0037679	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_012824388.2	Gene:	ulk1 / 100127200	XenbaseID:	XB-GENE-492029	Length:	1052	Species:	Xenopus tropicalis

Alignment Length:	269	Identity:	116/269 - (43%)
Similarity:	168/269 - (62%)	Gaps:	14/269 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FEILEK--LGAGSYATVYKARHK-KQRTYHAIKYVEMSTLSQTSRENLITEIRLLRELKHKYIVT 70
            ||...|  :|.|::|.|:|.||| ||....|:|.:....|:: |:..|..||::|:||||:.||.
Frog     7 FEFSRKDLIGHGAFAVVFKGRHKEKQDLEVAVKCINKKNLAK-SQTLLGKEIKILKELKHENIVA 70

  Fly    71 LQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKALPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQ 135
            |.||.....::|:|:||||.|:|:.::.|.:.|.|.|.|.||:|:|.|::.:.:..:.|.|||||
Frog    71 LYDFQELANSVYLVMEYCNGGDLADYLHTMRTLSEDTIRLFLQQIAGAMKMLHSKGIIHRDLKPQ 135

  Fly   136 NLLLT------RGANNVSLKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYDAKADLWSI 194
            |:||:      ...||:.:|:||||||::|:...:...|.|||:|||||::....||||||||||
Frog   136 NILLSCSGGRKSNPNNIRIKIADFGFARYLQNNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSI 200

  Fly   195 GVILYECLFGKAPYSSRTIEELLLRIRKAEAITLPPNARISNECH--DLLRRLLAHEPTARISFA 257
            |.|:|:||.||||:.:.:.::|.|...|.:.:|  ||......||  .||..||......|:.|.
Frog   201 GTIIYQCLTGKAPFQASSPQDLRLFYEKNKNLT--PNIPRETSCHLKQLLLGLLQRNQKDRMEFD 263

  Fly   258 DFFAHPFLD 266
            :||.|||||
Frog   264 EFFHHPFLD 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aduk	NP_731331.1	S_TKc	9..265	CDD:214567	113/266 (42%)
		PKc_like	13..264	CDD:304357	110/261 (42%)
		MIT_2	274..348	CDD:239147
		MIT	407..472	CDD:282117
ulk1	XP_012824388.2	STKc_ULK1	6..272	CDD:271104	114/267 (43%)
ulk1	XP_012824388.2	DUF3543	837..1047	CDD:403327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1084750at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5656
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950