Protein Alignment CG16749 and KLK4

DIOPT Version :9

• Sequence 1: NP_649881.1
• Gene: CG16749 / 41111
• FlyBaseID: FBgn0037678
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 79/259 - (30%)
• Similarity: 128/259 - (49%)
• Gaps: 32/259 - (12%)

  Fly    12 FALLTTAG--ISHGAPQMGRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQFVMTAAHCTD 74
            :.:|..||  :|....|   ::||.|.|....|:..:: .......|.|.::..|:|::||||..
Human    14 YLILGVAGSLVSGSCSQ---IINGEDCSPHSQPWQAAL-VMENELFCSGVLVHPQWVLSAAHCFQ 74

  Fly    75 GRKASDLSVQYGVTKINA---TGPNVVRVKKIIQHEDYN-PYNNYANDISLLLVEEPF-EFDGVT 134
                :..::..|:..:.|   .|..:|.....::|.:|| |.  .|||:.|:.::|.. |.|.:.
Human    75 ----NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPL--LANDLMLIKLDESVSESDTIR 133

  Fly   135 VAPVKLPELAFATPQTDAGGEGVLIGWGLNATGGYIQSTLQEVELKVYSDEECTERHGGRTDPRY 199
                   .::.|:....||...::.||||.| .|.:.:.||.|.:.|.|:|.|::.:    ||.|
Human   134 -------SISIASQCPTAGNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLY----DPLY 186

  Fly   200 H---ICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKKS 260
            |   .|.|..:..|..|:||||||||.||...|:||:...||.....||||..:.::.:||:|:
Human   187 HPSMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKT 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	29..257	CDD:214473	71/235 (30%)
		Tryp_SPc	30..259	CDD:238113	73/236 (31%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	73/237 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4287
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.970