DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG16749 and AZU1

DIOPT Version :9

Sequence 1:NP_649881.1 Gene:CG16749 / 41111 FlyBaseID:FBgn0037678 Length:265 Species:Drosophila melanogaster
Sequence 2:NP_001691.1 Gene:AZU1 / 566 HGNCID:913 Length:251 Species:Homo sapiens


Alignment Length:254 Identity:72/254 - (28%)
Similarity:116/254 - (45%) Gaps:23/254 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 LAVFALLT--TAGISHGAPQMGRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQFVMTAAH 71
            |.|.|||.  .|....|:..:..:|.|..:...::||:.|:: :.|.|.|||::|..:||||||.
Human     4 LTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQ-NQGRHFCGGALIHARFVMTAAS 67

  Fly    72 CTDGRKASDLSVQYGVTKINATGPNVVRVKKI--IQHEDYNPYNNYANDISLLLVEEPFEF-DGV 133
            |...:.....:|..|...:........:...|  :....|:|..| .||:.||.::..... ..|
Human    68 CFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQN-LNDLMLLQLDREANLTSSV 131

  Fly   134 TVAPVKLPELAFATPQTDAGGEGVLIGWGLNATGGYIQSTLQEVELKVYSDEECTERHGGRTDPR 198
            |:.|:.|..   ||  .:||....:.|||...:||.:....:.|.:.|..:::|...        
Human   132 TILPLPLQN---AT--VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN-------- 183

  Fly   199 YHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWI 257
             ::|.||.....|.|:||.|.||:..|...|:.|:|:.||  ...|..:.:|:.:.|||
Human   184 -NVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPC--GRGPDFFTRVALFRDWI 239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG16749NP_649881.1 Tryp_SPc 29..257 CDD:214473 63/230 (27%)
Tryp_SPc 30..259 CDD:238113 65/231 (28%)
AZU1NP_001691.1 Tryp_SPc 27..240 CDD:238113 65/231 (28%)
Possesses antibiotic activity. /evidence=ECO:0000269|PubMed:8506327 46..70 13/23 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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