DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG16749 and KLK10

DIOPT Version :9

Sequence 1:NP_649881.1 Gene:CG16749 / 41111 FlyBaseID:FBgn0037678 Length:265 Species:Drosophila melanogaster
Sequence 2:NP_001070968.1 Gene:KLK10 / 5655 HGNCID:6358 Length:276 Species:Homo sapiens


Alignment Length:257 Identity:70/257 - (27%)
Similarity:109/257 - (42%) Gaps:53/257 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    32 NGTDSSVEKY---------PFVISMRGSSGSHSCGGSIISKQFVMTAAHCTD----GRKASD--L 81
            |.|....|.|         |:.:|:......| |.|.::.:.:|:|||||.:    .|...|  |
Human    39 NDTRLDPEAYGSPCARGSQPWQVSLFNGLSFH-CAGVLVDQSWVLTAAHCGNKPLWARVGDDHLL 102

  Fly    82 SVQYGVTKINATGPNVVRVKKIIQHEDYN-------PYNNYANDISLLLVEEPFEFDGVTVAP-V 138
            .:|         |..:.|..:.:.|..|:       |.....:|:.||.:..|     |.:.| |
Human   103 LLQ---------GEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARP-----VVLGPRV 153

  Fly   139 KLPELAFATPQTDAGGEGVLIGWGLNA------TGGYIQSTLQEVELKVYSDEECTERHGGRTDP 197
            :..:|.:...|  .|.:..:.|||..|      ..|...|:     :.:.|.:||...:.|....
Human   154 RALQLPYRCAQ--PGDQCQVAGWGTTAARRVKYNKGLTCSS-----ITILSPKECEVFYPGVVTN 211

  Fly   198 RYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKK 259
            .. ||.|:|. |:..|..||||||:.:....||:||.:.||..|.:|.||.::.:|:.||.|
Human   212 NM-ICAGLDR-GQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINK 271

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG16749NP_649881.1 Tryp_SPc 29..257 CDD:214473 67/253 (26%)
Tryp_SPc 30..259 CDD:238113 69/255 (27%)
KLK10NP_001070968.1 Tryp_SPc 49..272 CDD:238113 66/247 (27%)
Tryp_SPc 49..269 CDD:214473 63/243 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 157 1.000 Inparanoid score I4287
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X21
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.970

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