Protein Alignment CG16749 and KLK6

DIOPT Version :9

• Sequence 1: NP_649881.1
• Gene: CG16749 / 41111
• FlyBaseID: FBgn0037678
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001012982.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 79/261 - (30%)
• Similarity: 121/261 - (46%)
• Gaps: 34/261 - (13%)

  Fly     9 LAVFALLTTAGISHGAPQMGRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQFVMTAAHCT 73
            :.|.:|:..|    .|.:..::|:|.......:|:..::. :||...|||.:|...:|:|||||
Human     5 MVVLSLIAAA----WAEEQNKLVHGGPCDKTSHPYQAALY-TSGHLLCGGVLIHPLWVLTAAHC- 63

  Fly    74 DGRKASDLSVQYGVTKI-----NATGPNVVRVKKIIQHEDYNPYNNYANDISLLLVEEPFEFDGV 133
               |..:|.|..|...:     :....:|||.   :.|.||:. .::..||.||.:
Human    64 ---KKPNLQVFLGKHNLRQRESSQEQSSVVRA---VIHPDYDA-ASHDQDIMLLRL--------- 112

  Fly   134 TVAPVKLPELAFATP-QTDAGGEGV---LIGWGLNATGGYIQSTLQEVELKVYSDEECTERHGGR 194
             ..|.||.||....| :.|......   ::|||..|.|.: ..|:|...:.:.|.|||...:.|:
Human   113 -ARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADGDF-PDTIQCAYIHLVSREECEHAYPGQ 175

  Fly   195 TDPRYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKK 259
            ..... :|.|.::.||..|.|||||||:......|:|||...||.....||||..|.:|.:||:|
Human   176 ITQNM-LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQK 239

  Fly   260 S 260
            :
Human   240 T 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	29..257	CDD:214473	72/236 (31%)
		Tryp_SPc	30..259	CDD:238113	74/237 (31%)
KLK6	NP_001012982.1	Tryp_SPc	23..237	CDD:214473	72/234 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4287
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8476
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.960