Protein Alignment CG16749 and PRSS2

DIOPT Version :9

• Sequence 1: NP_649881.1
• Gene: CG16749 / 41111
• FlyBaseID: FBgn0037678
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 92/261 - (35%)
• Similarity: 126/261 - (48%)
• Gaps: 28/261 - (10%)

  Fly    14 LLTTAGISHGAP--QMGRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQFVMTAAHCTDGR 76
            :||....:..||  ...::|.|........|:.:|:  :||.|.||||:||:|:|::|.||....
Human     6 ILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSL--NSGYHFCGGSLISEQWVVSAGHCYKSA 68

  Fly    77 KASDLS----------VQYGVTKINATGPN--VVRVKKIIQHEDYNPYNNYANDISLLLVEEPFE 129
            ..|.||          |:.|...|.....|  .:...|||:|..||. ....|||.|:.:..|..
Human    69 INSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNS-RTLDNDILLIKLSSPAV 132

  Fly   130 FDGVTVAPVKLPELAFATPQTDAGGEGVLIGWGLN-ATGGYIQSTLQEVELKVYSDEECTERHGG 193
            .:. .|:.:.||     |....||.|.::.|||.. ::|......||.::..|.|..||...:.|
Human   133 INS-RVSAISLP-----TAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPG 191

  Fly   194 R-TDPRYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWI 257
            : |:..:  |.|..||||..|.||||||::.||:..|||||.. .|.....||||.||..|||||
Human   192 KITNNMF--CVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGY-GCAQKNRPGVYTKVYNYVDWI 253

  Fly   258 K 258
            |
Human   254 K 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	29..257	CDD:214473	85/241 (35%)
		Tryp_SPc	30..259	CDD:238113	88/243 (36%)
PRSS2	NP_001290343.1	Tryp_SPc	23..253	CDD:214473	85/241 (35%)
		Tryp_SPc	24..256	CDD:238113	88/243 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8476
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920