DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG16749 and KLK14

DIOPT Version :9

Sequence 1:NP_649881.1 Gene:CG16749 / 41111 FlyBaseID:FBgn0037678 Length:265 Species:Drosophila melanogaster
Sequence 2:NP_001298111.2 Gene:KLK14 / 43847 HGNCID:6362 Length:251 Species:Homo sapiens


Alignment Length:258 Identity:80/258 - (31%)
Similarity:138/258 - (53%) Gaps:19/258 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 VFALLT-----TAGISHGAPQMGRVVNGTDSSVEKYPFVIS-MRGSSGSHSCGGSIISKQFVMTA 69
            :|.|||     ...::.......:::.|...:....|:..: :.|......|||:::|.|:|:||
Human     1 MFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITA 65

  Fly    70 AHCTDGRKASDLSV-QYGVTKINATGPNVVRVKKIIQHEDYNPYNNYANDISLLLVEEPFEFDGV 133
            |||  ||....::: ::.:.:..|| ..|:||.:.:.|.:||. ..:.||:.||.:::|... |.
Human    66 AHC--GRPILQVALGKHNLRRWEAT-QQVLRVVRQVTHPNYNS-RTHDNDLMLLQLQQPARI-GR 125

  Fly   134 TVAPVKLPELAFATPQTDAGGEGVLIGWG-LNATGGYIQSTLQEVELKVYSDEECTERHGGRTDP 197
            .|.|:::.: |.|:|.|...    :.||| :::......::||.|.:.:..||.|.:.: .||..
Human   126 AVRPIEVTQ-ACASPGTSCR----VSGWGTISSPIARYPASLQCVNINISPDEVCQKAY-PRTIT 184

  Fly   198 RYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKKS 260
            ...:|.||.:|||..|.|||||||:..||..|:|||.::.|.:..|||||..:.:|..||:::
Human   185 PGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEET 247

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG16749NP_649881.1 Tryp_SPc 29..257 CDD:214473 74/230 (32%)
Tryp_SPc 30..259 CDD:238113 76/231 (33%)
KLK14NP_001298111.2 Tryp_SPc 25..247 CDD:238113 76/232 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 157 1.000 Inparanoid score I4287
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8476
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X21
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.960

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