DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16749 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_649881.1	Gene:	CG16749 / 41111	FlyBaseID:	FBgn0037678	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	238	Identity:	75/238 - (31%)
Similarity:	119/238 - (50%)	Gaps:	20/238 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 RVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQFVMTAAHC-TDGRKASDLSVQYGVTKINA 92
            :|..|.|:...::|:..|:: .:..|.||.::||..:::||||| .......|..|.:|..   .
  Rat   186 KVAGGQDAEEGEWPWQASLQ-QNNVHRCGATLISNSWLITAAHCFVRSANPKDWKVSFGFL---L 246

  Fly    93 TGPNVVR-VKKIIQHEDYNPYNNYANDISLLLVEEPFEFDGVTVAPVKLPELAFATPQTDAGGEG 156
            :.|...| ||.|:.||:|: |..:.|||:::.:..|..::. .:....|||   ||.:.....:.
  Rat   247 SKPQAQRAVKSIVIHENYS-YPAHNNDIAVVRLSSPVLYEN-NIRRACLPE---ATQKFPPNSDV 306

  Fly   157 VLIGWGLNATGGYIQSTLQEVELKVYSDEECT--ERHGGRTDPRYHICGGVDEGGKGQCSGDSGG 219
            |:.|||...:.|...:.||:..:|:..::.|.  :.:||...|.. :|.|..||....|.|||||
  Rat   307 VVTGWGTLKSDGDSPNILQKGRVKIIDNKTCNSGKAYGGVITPGM-LCAGFLEGRVDACQGDSGG 370

  Fly   220 PLIYNGQQ-----VGIVSWSIKPCTVAPYPGVYCKVSQYVDWI 257
            ||:....:     .|||||. ..|.:...||||.:|:.|.|||
  Rat   371 PLVSEDSKGIWFLAGIVSWG-DECALPNKPGVYTRVTHYRDWI 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	29..257	CDD:214473	73/236 (31%)
CG16749	NP_649881.1	Tryp_SPc	30..259	CDD:238113	75/237 (32%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	73/236 (31%)
		Tryp_SPc	187..415	CDD:238113	75/237 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010