Protein Alignment CG16749 and KLK2

DIOPT Version :9

• Sequence 1: NP_649881.1
• Gene: CG16749 / 41111
• FlyBaseID: FBgn0037678
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 75/260 - (28%)
• Similarity: 127/260 - (48%)
• Gaps: 22/260 - (8%)

  Fly    11 VFALLTTAGISHGAPQM-GRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQFVMTAAHCTD 74
            |.::..:.|.:...|.: .|:|.|.:......|:.:::.....:| |||.::..|:|:|||||.
Human     5 VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAH-CGGVLVHPQWVLTAAHCL- 67

  Fly    75 GRKASDLSV-QYGVTKINATG---------PNVVRVKKIIQHEDYNPYNNYANDISLLLVEEPFE 129
             :|.|.:.: ::.:.:...||         |:.:....:::|:...|..:.::|:.||.:.||.:
Human    68 -KKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAK 131

  Fly   130 FDGVTVAPVKLPELAFATPQTDAGGEGVLIGWGLNATGGYIQ-STLQEVELKVYSDEECTERHGG 193
            ...|    ||:  |...|.:...|......|||......::: .:||.|.|.:.|::.|...:..
Human   132 ITDV----VKV--LGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190

  Fly   194 RTDPRYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIK 258
            :. ..:.:|.|:..|||..|.|||||||:.||...||.||..:||.:...|.||.||..|..|||
Human   191 KV-TEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIK 254

  Fly   259  258
            Human   255  254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	29..257	CDD:214473	69/238 (29%)
		Tryp_SPc	30..259	CDD:238113	71/240 (30%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	71/240 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4287
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8476
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.960