Protein Alignment CG16749 and KLK1

DIOPT Version :9

• Sequence 1: NP_649881.1
• Gene: CG16749 / 41111
• FlyBaseID: FBgn0037678
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 85/268 - (31%)
• Similarity: 126/268 - (47%)
• Gaps: 34/268 - (12%)

  Fly     7 LCLAVFALLTTAGISHGAPQMGRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQFVMTAAH 71
            ||||    |:..|.....|...|:|.|.:......|:..::...| :..|||.::.:|:|:||||
Human     6 LCLA----LSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFS-TFQCGGILVHRQWVLTAAH 65

  Fly    72 CTDGRKASDLSVQYGVTKIN----ATGPNVVRVKKIIQHEDYN----------PYNNYANDISLL 122
            |     .|| :.|..:.:.|    ......|.|.:...|..:|          ...:|::|:.||
Human    66 C-----ISD-NYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLL 124

  Fly   123 LVEEPFEFDGVTVAPVKLPELAFATPQTDAGGEGVLIGWG-LNATGGYIQSTLQEVELKVYSDEE 186
            .:.||  .|.:|.| ||:.||  .|.:.:.|...:..||| :..........||.|:||:..::|
Human   125 RLTEP--ADTITDA-VKVVEL--PTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDE 184

  Fly   187 CTERHGGR-TDPRYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKV 250
            |.:.|..: ||  :.:|.|..||||..|.|||||||:.:|...|:.||...||.....|.|..:|
Human   185 CKKAHVQKVTD--FMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRV 247

  Fly   251 SQYVDWIK 258
            ..||.||:
Human   248 LSYVKWIE 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	29..257	CDD:214473	76/243 (31%)
		Tryp_SPc	30..259	CDD:238113	77/245 (31%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	77/245 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4287
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8476
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.960