DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16749 and CG30371

DIOPT Version :9

Sequence 1:	NP_649881.1	Gene:	CG16749 / 41111	FlyBaseID:	FBgn0037678	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_610370.1	Gene:	CG30371 / 35806	FlyBaseID:	FBgn0050371	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	76/294 - (25%)
Similarity:	142/294 - (48%)	Gaps:	46/294 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRNQDLCLAVFALLTTA---------------GISHGAPQMGRVVNGTDSSVEKYPFVISMRGS 50
            :||.......|||.::|.               ..:.|.....|:.||..::..::|.:.:::..
  Fly   106 LSRESLFTELVFAYISTGTKGGSFKCTLTTVKQNCNCGWSATTRIANGQQAAANEFPSMAALKDV 170

  Fly    51 SGSHS--CGGSIISKQFVMTAAHCT-DGRKASDLSVQYGVTKINATGPNVVR------VKKIIQH 106
            :.:.:  |||:|::.::::|||||. ...:|:::....|...:.  .|:..|      ::::|.|
  Fly   171 TKNQASFCGGTIVAHRYILTAAHCIYQVSRATNIVAIVGTNDLG--NPSSSRYYQQYNIQQMIPH 233

  Fly   107 EDYNPYNNYANDISLLLVEEPFEFDGVTVAPVKLPELAFATPQT----DAGGEGVLIGWGLNATG 167
            |.|....:..|||::|:.....::.. .|.|:.||.:..:||.|    |      :||:|.....
  Fly   234 EQYVSDPDVNNDIAVLITASNIQWSR-GVGPICLPPVGTSTPFTYDLVD------VIGYGTVFFA 291

  Fly   168 GYIQSTLQEVELKVYSDEEC-TERHGGRTDPRYHICGGVDEGGKGQ--CSGDSGGPLIYNGQQ-- 227
            |...::||::.|.|.::::| ||.:...|.....:| ..|..|.|:  |..|||||:|....:
  Fly   292 GPTSTSLQKINLNVVTNQDCQTEYNNVATIYTGQMC-TYDYSGTGRDSCQFDSGGPVILRKSRQF 355

  Fly   228 -VGIVSWSIKPCTVAPYP-GVYCKVSQYVDWIKK 259
             |||:|:. |.|..:.|| ||..:::.|:.||::
  Fly   356 LVGIISYG-KSCAESQYPMGVNTRITSYISWIRQ 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	29..257	CDD:214473	67/247 (27%)
CG16749	NP_649881.1	Tryp_SPc	30..259	CDD:238113	68/248 (27%)
CG30371	NP_610370.1	CUB	24..>67	CDD:294042
		Tryp_SPc	149..386	CDD:214473	67/247 (27%)
		Tryp_SPc	150..389	CDD:238113	68/250 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456011
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930