Protein Alignment CG16749 and KLK3

DIOPT Version :10

• Sequence 1: NP_649881.1
• Gene: CG16749 / 41111
• FlyBaseID: FBgn0037678
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 82/260 - (31%)
• Similarity: 121/260 - (46%)
• Gaps: 23/260 - (8%)

  Fly    11 VFALLTTAGISHGAPQMGRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQFVMTAAHCTDG 75
            ||..|:...|......:.|:|.|.:......|:.: :..|.|...|||.::..|:|:|||||. .
Human     6 VFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQV-LVASRGRAVCGGVLVHPQWVLTAAHCI-R 68

  Fly    76 RKASDLSVQYGVTKINATGPNVVRVKKIIQHEDYN----------PYNNYANDISLLLVEEPFEF 130
            .|:..|..::.:.....|| .|.:|.....|..|:          |.::.::|:.||.:.||.|.
Human    69 NKSVILLGRHSLFHPEDTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL 132

  Fly   131 -DGVTVAPVKLPELAFATPQTDAGGEGVLIGWGLNATGGYI-QSTLQEVELKVYSDEECTERHGG 193
             |.|.|..:...|.|..|....:       |||......:: ...||.|:|.|.|::.|.:.|..
Human   133 TDAVKVMDLPTQEPALGTTCYAS-------GWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ 190

  Fly   194 RTDPRYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIK 258
            :. .::.:|.|...|||..|||||||||:.||...||.||..:||.:...|.:|.||..|..|||
Human   191 KV-TKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 254

  Fly   259  258
            Human   255  254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	30..259	CDD:238113	77/241 (32%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	77/241 (32%)