DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG16749 and KLK3

DIOPT Version :9

Sequence 1:NP_649881.1 Gene:CG16749 / 41111 FlyBaseID:FBgn0037678 Length:265 Species:Drosophila melanogaster
Sequence 2:NP_001639.1 Gene:KLK3 / 354 HGNCID:6364 Length:261 Species:Homo sapiens


Alignment Length:260 Identity:82/260 - (31%)
Similarity:121/260 - (46%) Gaps:23/260 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 VFALLTTAGISHGAPQMGRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQFVMTAAHCTDG 75
            ||..|:...|......:.|:|.|.:......|:.: :..|.|...|||.::..|:|:|||||. .
Human     6 VFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQV-LVASRGRAVCGGVLVHPQWVLTAAHCI-R 68

  Fly    76 RKASDLSVQYGVTKINATGPNVVRVKKIIQHEDYN----------PYNNYANDISLLLVEEPFEF 130
            .|:..|..::.:.....|| .|.:|.....|..|:          |.::.::|:.||.:.||.|.
Human    69 NKSVILLGRHSLFHPEDTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL 132

  Fly   131 -DGVTVAPVKLPELAFATPQTDAGGEGVLIGWGLNATGGYI-QSTLQEVELKVYSDEECTERHGG 193
             |.|.|..:...|.|..|....:       |||......:: ...||.|:|.|.|::.|.:.|..
Human   133 TDAVKVMDLPTQEPALGTTCYAS-------GWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ 190

  Fly   194 RTDPRYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIK 258
            :. .::.:|.|...|||..|||||||||:.||...||.||..:||.:...|.:|.||..|..|||
Human   191 KV-TKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 254

  Fly   259  258
            Human   255  254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG16749NP_649881.1 Tryp_SPc 29..257 CDD:214473 75/239 (31%)
Tryp_SPc 30..259 CDD:238113 77/241 (32%)
KLK3NP_001639.1 Tryp_SPc 25..256 CDD:238113 77/241 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 157 1.000 Inparanoid score I4287
Isobase 1 0.950 - 0 Normalized mean entropy S8278
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8476
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X21
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
65.920

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