Protein Alignment CG16749 and PRSS33

DIOPT Version :10

• Sequence 1: NP_649881.1
• Gene: CG16749 / 41111
• FlyBaseID: FBgn0037678
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_690851.2
• Gene: PRSS33 / 260429
• HGNCID: 30405
• Length: 280
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 89/285 - (31%)
• Similarity: 129/285 - (45%)
• Gaps: 49/285 - (17%)

  Fly     8 CLAVFALLT-----TAG---ISHGAPQM-GRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISK 63
            ||.|..||.     |.|   .:.|.|:| .|:|.|.|....::|:..|:: ..|:|.||||:|:.
Human     6 CLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQ-HRGAHVCGGSLIAP 69

  Fly    64 QFVMTAAHCTDGRK-ASDLSVQYGVTKINATGPNV--VRVKKIIQHEDYNPYNNYANDISLLLVE 125
            |:|:|||||...|. .::..|:.|..::.:|.|..  |.|::::...||:. :....|::||.:.
Human    70 QWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSE-DGARGDLALLQLR 133

  Fly   126 EPFEFDGVTVAPVKLPELAFATPQTDAGGEGVLIGWGLNATGGYIQS--TLQEVELKVYSDEECT 188
            .|... ...|.||.||......|   .|....:.|||....|..:..  .||.|.:.:.....|
Human   134 RPVPL-SARVQPVCLPVPGARPP---PGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTC- 193

  Fly   189 ERHGGRTDPRYHI----------------CGGVDEGGKGQCSGDSGGPL--IYNGQ--QVGIVSW 233
                   |..||:                |.|..:|.|..|.|||||||  :.:|.  .||:|||
Human   194 -------DGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSW 251

  Fly   234 SIKPCTVAPYPGVYCKVSQYVDWIK 258
            . |.|.:...||||..|:.|..||:
Human   252 G-KGCALPNRPGVYTSVATYSPWIQ 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	30..259	CDD:238113	78/254 (31%)
PRSS33	NP_690851.2	Tryp_SPc	37..275	CDD:238113	77/252 (31%)