Protein Alignment CG16749 and KLK5

DIOPT Version :10

• Sequence 1: NP_649881.1
• Gene: CG16749 / 41111
• FlyBaseID: FBgn0037678
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 68/263 - (25%)
• Similarity: 123/263 - (46%)
• Gaps: 27/263 - (10%)

  Fly     4 NQDLCLAVFALLTTAGISHGA---PQMGRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQF 65
            ||||         .||....|   ....|::||:|..:...|:..::........||..::..|:
Human    47 NQDL---------GAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQW 102

  Fly    66 VMTAAHCTDGRKASDLSV-QYGVTKINATGPNVVRVKKIIQHEDYNPYNNYANDISLLLVEEPFE 129
            ::|||||.  :|...:.: .|.::.:..:|..:.:..|.|.|..|: :..::||:.|:.:..
Human   103 LLTAAHCR--KKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYS-HPGHSNDLMLIKLNR--- 161

  Fly   130 FDGVTVAPVK-LPELAFATPQTDAGGEGVLIGWGLNATGG-YIQSTLQEVELKVYSDEECTERHG 192
                .:.|.| :..:..::....||.:.::.|||...:.. :....||.:.:.|.|.:.|.:.:.
Human   162 ----RIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYP 222

  Fly   193 GRTDPRYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWI 257
            .:.|... .|.| |:.|:..|.||||||::.||...|:|||...||.....||||..:.::..||
Human   223 RQIDDTM-FCAG-DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWI 285

  Fly   258 KKS 260
            :::
Human   286 QET 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	30..259	CDD:238113	60/231 (26%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		8/29 (28%)
		Tryp_SPc	66..285	CDD:214473	59/230 (26%)