Protein Alignment CG16749 and KLK5

DIOPT Version :9

• Sequence 1: NP_649881.1
• Gene: CG16749 / 41111
• FlyBaseID: FBgn0037678
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001070959.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 68/263 - (25%)
• Similarity: 123/263 - (46%)
• Gaps: 27/263 - (10%)

  Fly     4 NQDLCLAVFALLTTAGISHGA---PQMGRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQF 65
            ||||         .||....|   ....|::||:|..:...|:..::........||..::..|:
Human    47 NQDL---------GAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQW 102

  Fly    66 VMTAAHCTDGRKASDLSV-QYGVTKINATGPNVVRVKKIIQHEDYNPYNNYANDISLLLVEEPFE 129
            ::|||||.  :|...:.: .|.::.:..:|..:.:..|.|.|..|: :..::||:.|:.:..
Human   103 LLTAAHCR--KKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYS-HPGHSNDLMLIKLNR--- 161

  Fly   130 FDGVTVAPVK-LPELAFATPQTDAGGEGVLIGWGLNATGG-YIQSTLQEVELKVYSDEECTERHG 192
                .:.|.| :..:..::....||.:.::.|||...:.. :....||.:.:.|.|.:.|.:.:.
Human   162 ----RIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYP 222

  Fly   193 GRTDPRYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWI 257
            .:.|... .|.| |:.|:..|.||||||::.||...|:|||...||.....||||..:.::..||
Human   223 RQIDDTM-FCAG-DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWI 285

  Fly   258 KKS 260
            :::
Human   286 QET 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	29..257	CDD:214473	59/230 (26%)
		Tryp_SPc	30..259	CDD:238113	60/231 (26%)
KLK5	NP_001070959.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		8/29 (28%)
		Tryp_SPc	66..285	CDD:214473	59/230 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4287
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8476
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.960