DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16749 and Habp2

DIOPT Version :9

Sequence 1:	NP_649881.1	Gene:	CG16749 / 41111	FlyBaseID:	FBgn0037678	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001316864.1	Gene:	Habp2 / 226243	MGIID:	1196378	Length:	554	Species:	Mus musculus

Alignment Length:	256	Identity:	80/256 - (31%)
Similarity:	122/256 - (47%)	Gaps:	43/256 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 RVVNGTDSSVEKYPFVISMRGS-------SGSHSCGGSIISKQFVMTAAHCTDGRKASDLSVQYG 86
            |:..|..|:..|:|:.:|::.|       ...|.|||::|...:|:||||||| .....|.|..|
Mouse   307 RIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGALIHPCWVLTAAHCTD-INTKHLKVVLG 370

  Fly    87 VTKINATGPN--VVRVKKIIQHEDYNPYNNYA-NDISLLLVEEPF----EFDGVTVAPVKLPELA 144
            ...:..|..:  ..||:||:::..||..:... |||:||.: :|.    ..:...|..|.||...
Mouse   371 DQDLKKTESHEQTFRVEKILKYSQYNERDEIPHNDIALLKL-KPVGGHCALESRYVKTVCLPSDP 434

  Fly   145 FATPQTDAGGEGVLIGWGLNATG-GYIQSTLQEVELKVYSDEECTER--HGGRTDPRYHICGGVD 206
            |     .:|.|..:.|||:..|| |..|  |.:.::|:.::..|..|  :....|......|.:.
Mouse   435 F-----PSGTECHISGWGVTETGEGSRQ--LLDAKVKLIANPLCNSRQLYDHTIDDSMICAGNLQ 492

  Fly   207 EGGKGQCSGDSGGPL---------IYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIK 258
            :.|...|.|||||||         :|     |||||. :.|  ...||||.:|:::::|||
Mouse   493 KPGSDTCQGDSGGPLTCEKDGTYYVY-----GIVSWG-QEC--GKKPGVYTQVTKFLNWIK 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	29..257	CDD:214473	77/253 (30%)
CG16749	NP_649881.1	Tryp_SPc	30..259	CDD:238113	79/255 (31%)
Habp2	NP_001316864.1	EGF_CA	67..103	CDD:238011
		EGF_CA	150..182	CDD:238011
		KR	187..271	CDD:238056
		Tryp_SPc	308..547	CDD:238113	79/255 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000