DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16749 and Klk1b8

DIOPT Version :9

Sequence 1:	NP_649881.1	Gene:	CG16749 / 41111	FlyBaseID:	FBgn0037678	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_032483.1	Gene:	Klk1b8 / 16624	MGIID:	892018	Length:	261	Species:	Mus musculus

Alignment Length:	264	Identity:	79/264 - (29%)
Similarity:	116/264 - (43%)	Gaps:	27/264 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LAVFALLTTAGISHGAPQMGRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQFVMTAAHCT 73
            |.:|..|:..||....|...|||.|.:......|:.:::..:. .|.|||.::.:.:|:|||||
Mouse     4 LILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNK-EHICGGVLLERNWVLTAAHC- 66

  Fly    74 DGRKASDLSVQYGVTKINATGPNVVR--VKKIIQHEDYN----------PYNNYANDISLLLVEE 126
               ......|..|..|:....|:...  |.|...|..:|          |..:::||:.||.:.:
Mouse    67 ---YVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSK 128

  Fly   127 PFEFDGVTVAPVKLPELAFATPQTDAGGEGVLIGWG-LNATGGYIQSTLQEVELKVYSDEECTER 190
            |.:... .|.|:.||     |.::..|...:..||| :..|.......||.|.||:...:.|.|.
Mouse   129 PADITD-AVKPITLP-----TKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIEN 187

  Fly   191 HGGR-TDPRYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYV 254
            |..: ||  ..:|.|...|||..|.||||||||.:....||.|....||.....|.:|..:.::.
Mouse   188 HNVKVTD--VMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFN 250

  Fly   255 DWIK 258
            .|||
Mouse   251 SWIK 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	29..257	CDD:214473	70/241 (29%)
CG16749	NP_649881.1	Tryp_SPc	30..259	CDD:238113	72/243 (30%)
Klk1b8	NP_032483.1	Tryp_SPc	24..253	CDD:214473	70/241 (29%)
Klk1b8	NP_032483.1	Tryp_SPc	25..256	CDD:238113	72/243 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I4246
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.050