Protein Alignment CG16749 and KLK11

DIOPT Version :10

• Sequence 1: NP_649881.1
• Gene: CG16749 / 41111
• FlyBaseID: FBgn0037678
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 79/284 - (27%)
• Similarity: 128/284 - (45%)
• Gaps: 46/284 - (16%)

  Fly     7 LCLAVFALLTTAGISHGAPQMGRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQFVMTAAH 71
            |.|.:.||.|  |:..|..   |::.|.:......|:..::...: ...||.::|:.::::||||
Human    36 LQLILLALAT--GLVGGET---RIIKGFECKPHSQPWQAALFEKT-RLLCGATLIAPRWLLTAAH 94

  Fly    72 C--------TDGRKASDLSV----------------QYGVTKINATGPNVVR-VKKIIQHEDYN- 110
            |        :....:.|||.                |:.:.|  ..|....| ..:...|..:|
Human    95 CLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQK--EEGCEQTRTATESFPHPGFNN 157

  Fly   111 --PYNNYANDISLLLVEEPFEFDGVTVAPVKLPELAFATPQTDAGGEGVLIGWGLNATGGY-IQS 172
              |..::.|||.|:.:..|     |::.....| |..::....||...::.|||..::... :..
Human   158 SLPNKDHRNDIMLVKMASP-----VSITWAVRP-LTLSSRCVTAGTSCLISGWGSTSSPQLRLPH 216

  Fly   173 TLQEVELKVYSDEECTERHGGR-TDPRYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIK 236
            ||:...:.:...::|...:.|. ||..  :|..|.||||..|.|||||||:.|....||:||...
Human   217 TLRCANITIIEHQKCENAYPGNITDTM--VCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQD 279

  Fly   237 PCTVAPYPGVYCKVSQYVDWIKKS 260
            ||.:...||||.||.:|||||:::
Human   280 PCAITRKPGVYTKVCKYVDWIQET 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	30..259	CDD:238113	71/258 (28%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	70/257 (27%)