DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16749 and Klk9

DIOPT Version :9

Sequence 1:	NP_649881.1	Gene:	CG16749 / 41111	FlyBaseID:	FBgn0037678	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_082936.2	Gene:	Klk9 / 101533	MGIID:	1921082	Length:	251	Species:	Mus musculus

Alignment Length:	212	Identity:	66/212 - (31%)
Similarity:	106/212 - (50%)	Gaps:	19/212 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 CGGSIISKQFVMTAAHCTDGRKASDLSVQYGVTKI-NATGP-NVVRVKKIIQHEDYNP---YNNY 115
            ||.::|:.|:::|||||   ||.. |.|:.|...: ...|| .::.|.....|..:||   .|::
Mouse    48 CGATLINDQWLLTAAHC---RKPY-LWVRLGEHHLWRWEGPEQLLLVTDFFPHPGFNPDLSANDH 108

  Fly   116 ANDISLLLVEEPFEFDGVTVAPVKLPELAFATPQTDAGGEGVLIGWGLNATGGYIQ--STLQEVE 178
            .:||.|:.:...     |.:.|...| |.....:...|.:.::.||| :.:...:|  .|||...
Mouse   109 NDDIMLIRLPRK-----VRLTPAVQP-LNLTESRPPVGTQCLISGWG-SVSSSKLQYPMTLQCAN 166

  Fly   179 LKVYSDEECTERHGGRTDPRYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPY 243
            :.:..::.|...:.|....:. :|.|:.|||:|.|.|||||||:..|...||||...:||:....
Mouse   167 ISILDNKLCRWAYPGHISEKM-LCAGLWEGGRGSCQGDSGGPLVCEGTLAGIVSGGSEPCSRPRR 230

  Fly   244 PGVYCKVSQYVDWIKKS 260
            |.||..|..|::||:.:
Mouse   231 PAVYTNVFDYLEWIEST 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16749	NP_649881.1	Tryp_SPc	29..257	CDD:214473	64/207 (31%)
CG16749	NP_649881.1	Tryp_SPc	30..259	CDD:238113	66/209 (32%)
Klk9	NP_082936.2	Tryp_SPc	24..247	CDD:238113	66/210 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I4246
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.970