DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12951 and st14b

DIOPT Version :9

Sequence 1:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_005161261.1	Gene:	st14b / 777629	ZFINID:	ZDB-GENE-061103-613	Length:	864	Species:	Danio rerio

Alignment Length:	251	Identity:	79/251 - (31%)
Similarity:	120/251 - (47%)	Gaps:	20/251 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GQAAPSISRVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISKHFVMTAAHCTNGR------PAD 79
            |:.....||:|.|.||...::|:.|||......|.||.|:||..:::|||||....      .||
Zfish   616 GKKPHKSSRIVGGKDSDEGEWPWQVSLHMKTQGHVCGASVISNSWLVTAAHCVQDNDQFRYSQAD 680

  Fly    80 TLSIQFGVTNISAMGPNVV-GIKKIIQHEDFDPTRQNANDISLLMVEEPFEFDGVSVAPVELPAL 143
            ...:..|:.|......:.. .:.:||.|..:|.:..: |||:|:.::.|...: .::.|:.||..
Zfish   681 QWEVYLGLHNQGETSKSTQRSVLRIIPHPQYDHSSYD-NDIALMELDSPVTLN-QNIWPICLPDP 743

  Fly   144 AFAVPQSDAGVEGVLIGWG-LNDTYGSVQDTLQEVSLKIYSDEECTSRHNGQTDPKYHICGGVDE 207
            ....|   ||....:.||| |.:...:|...||:..::|.:...|:...:....| :.||.||..
Zfish   744 THYFP---AGKSVWITGWGKLREGSDAVPSVLQKAEVRIINSTVCSKLMDDGITP-HMICAGVLS 804

  Fly   208 GGKGQCSGDSGGPLIY---NGQQ--VGIVSWSIKPCTVAPYPGVYCKVSQYVDWIK 258
            ||...|.||||||:..   ||:.  .|:|||. ..|.....||||.:|:.|..||:
Zfish   805 GGVDACQGDSGGPMSSIEGNGRMFLAGVVSWG-DGCGRRNRPGVYTRVTDYRSWIR 859

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	75/240 (31%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	76/242 (31%)
st14b	XP_005161261.1	SEA	92..180	CDD:279699
		CUB	233..342	CDD:238001
		CUB	351..457	CDD:238001
		LDLa	465..497	CDD:238060
		LDLa	499..533	CDD:238060
		LDLa	536..570	CDD:238060
		LDLa	578..613	CDD:238060
		Tryp_SPc	624..858	CDD:214473	75/240 (31%)
		Tryp_SPc	625..861	CDD:238113	76/242 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920