Protein Alignment CG12951 and Prss8

DIOPT Version :10

• Sequence 1: NP_649880.1
• Gene: CG12951 / 41110
• FlyBaseID: FBgn0037677
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_579929.1
• Gene: Prss8 / 76560
• MGIID: 1923810
• Length: 339
• Species: Mus musculus
• Alignment Length: 277
• Identity: 79/277 - (28%)
• Similarity: 131/277 - (47%)
• Gaps: 36/277 - (12%)

  Fly     8 SLSLIVILAVTTVGQAAPSIS---------RVVNGTDSSVLKYPFVVSLRSYDGSHSCGGSIISK 63
            :::::::|.:...|..|....         |:..|..:...::|:.||: :|||:|.||||::|.
Mouse    14 AVTILLLLGLLQSGIRADGTEASCGAVIQPRITGGGSAKPGQWPWQVSI-TYDGNHVCGGSLVSN 77

  Fly    64 HFVMTAAHC-TNGRPADTLSIQFGVTNISAMGPNVV--GIKKIIQHEDFDPTRQNAN--DISLLM 123
            .:|::|||| ......:...::.|...:.:...:.|  .:.:||.|..:   |:..:  ||:|:.
Mouse    78 KWVVSAAHCFPREHSREAYEVKLGAHQLDSYSNDTVVHTVAQIITHSSY---REEGSQGDIALIR 139

  Fly   124 VEEPFEFDGVSVAPVELPALAFAVPQSDAGVEGVLIGWGLNDTYGSVQD--TLQEVSLKIYSDEE 186
            :..|..|... :.|:.|||...:.|.   |:...:.|||......|:|.  .||::.:.:.|.|.
Mouse   140 LSSPVTFSRY-IRPICLPAANASFPN---GLHCTVTGWGHVAPSVSLQTPRPLQQLEVPLISRET 200

  Fly   187 CTSRHNGQTDPKY-H------ICGGVDEGGKGQCSGDSGGPLIYNGQQV----GIVSWSIKPCTV 240
            |:..:|....|:. |      :|.|..:|||..|.|||||||....:.:    |||||. ..|..
Mouse   201 CSCLYNINAVPEEPHTIQQDMLCAGYVKGGKDACQGDSGGPLSCPMEGIWYLAGIVSWG-DACGA 264

  Fly   241 APYPGVYCKVSQYVDWI 257
            ...||||...|.|..||
Mouse   265 PNRPGVYTLTSTYASWI 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	75/246 (30%)
Prss8	NP_579929.1	Tryp_SPc	45..284	CDD:238113	75/246 (30%)